Could stem cell drops replace surgery for dry eye and cataract?
NCT ID NCT07191847
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests special eye drops made with stem cells to see if they can help people with dry eye disease and cataracts. Researchers will give 300 adults these drops three times a day for 12 weeks. They will check if the drops improve tear film, reduce symptoms, and clear up the eye's lens.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- stem cell-fortified eye drops
- What this could lead to
- If it works, this could offer a new non-surgical option to manage dry eye and early cataract symptoms, improving comfort and vision.
- What could go wrong
- This is a Phase 4 trial, but the intervention is still experimental. Results may not show clear benefit, and individual responses can vary. Risks include eye irritation or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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Jan 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-80 years. * Diagnosed with dry eye disease (based on clinical criteria such as OSDI scores and Schirmer test results). Exclusion Criteria: * Exclusion Criteria: * History of ocular surgery or trauma. * Other ocular diseases (e.g., glaucoma, keratitis). * Systemic conditions that may interfere with study outcomes (e.g., autoimmune diseases).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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British center for regenerative medicine
RECRUITINGGiza, 335019, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- One operation for cataract and glaucoma? eye surgeons test a Two-in-One approach
- Can a 13-Minute eye exercise routine ease screen strain?
- Eye drops may shield the cornea after cataract surgery
- Gel plug in tear duct tested to keep eyes moist after cataract surgery
- A gel plug for tear ducts may stop post-surgery dry eye