CARDIOGENIC SHOCK

This study looks at whether giving people a heart-lung machine (ECMO) right where they collapse from a cardiac arrest can improve survival and brain function. About 90 adults under 70 who have a witnessed arrest and receive bystander CPR will be included. The goal is to see if st…

This study tests whether adding a special heart pump (IABP) helps people on ECMO recover from severe cardiogenic shock. About 430 adults will be randomly assigned to get ECMO alone or ECMO plus the pump. The main goal is to see if more patients can successfully come off ECMO with…

This study tests whether setting a personalized blood pressure goal based on each patient's condition improves outcomes for adults in cardiogenic shock, a life-threatening state where the heart can't pump enough blood. About 406 participants will be randomly assigned to either st…

This study tests the Cardiohelp device, a heart-lung machine, in up to 50 children with severe heart failure to see if it is safe and effective for up to 30 days. It also compares two blood thinners, heparin and bivalirudin, to find which causes fewer bleeding or clotting problem…

This study tests whether using a heart-lung machine (ECMO) before a high-risk aortic valve replacement can prevent death, cardiac arrest, or emergency surgery. It includes 30 adults with severe aortic stenosis who are unstable or have complex anatomy. Participants receive ECMO su…

This study tests a temporary heart pump (iVAC 2L) in 100 people with severe coronary artery disease who need high-risk angioplasty. The pump helps keep blood flowing during the procedure, which may reduce the chance of death, heart attack, or stroke. The goal is to see if the dev…

This study looks at 408 adults with severe heart failure (cardiogenic shock) who need a heart-lung machine (ECMO) and have kidney injury. It compares starting kidney dialysis early versus waiting for standard timing. The goal is to see which approach reduces the chance of death o…

This study follows 350 people who survived cardiogenic shock (a severe heart condition) after leaving the hospital. Researchers want to see how many survive or need to be readmitted over time. The goal is to learn what challenges patients face and build better support systems for…

This study looks back at medical records of 3,000 people with cardiogenic shock, a life-threatening condition where the heart suddenly can't pump enough blood. Researchers want to see if survival rates improved after a special shock team started working at the hospital in 2017. N…

This study looks at 600 adults hospitalized with acute heart failure or cardiogenic shock. Researchers want to see if information from standard hospital care, plus blood and urine samples, can help predict who is at higher risk of dying within 30 days. No experimental treatment i…

This study is observing 1000 adults hospitalized with acute heart failure to learn how to better predict their recovery and future risks. Researchers will analyze blood markers, imaging, and other health data. The goal is to improve care for people with this serious heart conditi…

This study is a registry that will collect data from 3,000 people hospitalized with cardiogenic shock, a life-threatening condition where the heart suddenly cannot pump enough blood. Researchers aim to understand patient profiles, treatments, and outcomes over time. No experiment…

This study is for adults in cardiogenic shock who need a temporary heart pump called an intra-aortic balloon pump. Researchers want to see if the stiffness of a person's arteries affects how well the pump works. They will measure blood flow and other vital signs before and after …

This study collects blood samples from 300 people with cardiogenic shock (a severe heart condition) to analyze their genes and immune markers. The goal is to find patterns that explain why some patients respond differently to treatment. No new treatment is given; this is purely o…