Could less be more? new trial aims to save lives by using less blood pressure medication in shock
NCT ID NCT05168462
First seen Mar 27, 2026 · Last updated May 22, 2026 · Updated 9 times
Summary
This study looks at whether using less of the drug noradrenaline by aiming for a lower blood pressure (≥55 mmHg) can improve survival and reduce severe kidney failure in people with cardiogenic shock after a heart attack. About 776 adults who have had a heart attack and are in shock will be randomly assigned to either the lower blood pressure target or the standard target (≥65 mmHg). The main goal is to see if the lower target reduces the chance of death or the need for kidney dialysis within 30 days.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amsterdam UMC, location AMC
RECRUITINGAmsterdam, 1105AZ, Netherlands
Contact Email: •••••@•••••
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