New study aims to decode deadly heart shock using simple blood and urine tests
NCT ID NCT07515508
First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times
Summary
This observational study will follow 600 adults hospitalized with acute heart failure or cardiogenic shock. Researchers will collect information from routine care, plus extra blood and urine samples, to see if they can better identify different types of shock and predict who is at highest risk of dying within 30 days. No experimental treatment is given; the goal is simply to learn more about the condition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better identify different types of cardiogenic shock and predict which patients are at higher risk, potentially guiding more personalized care.
- What could go wrong
- This is an observational study, not a treatment trial. It collects data but does not test any new therapy, so it cannot directly improve outcomes. Results may not change current practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 600 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2024
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Consecutive adult patients hospitalized at participating study sites with acute heart failure and cardiogenic shock (SCAI stages B-E).
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients hospitalized with acute heart failure SCAI stage B - E. Exclusion Criteria: * Not capable of providing informed consent due to reasons not attributable to cardiogenic shock * Cardiogenic shock following cardiothoracic surgery
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department for Internal Medicine 8, Clinic for Cardiology and Rhythmology, University Clinic of the Paracelsus Medi-cal University Nuremberg
RECRUITINGNuremberg, Germany
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Schwarzwald Baar Klinikum Villingen-Schwenningen, Klinik für Kardiologie und Intensivmedizin
RECRUITINGVillingen-Schwenningen, Germany
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University Heart Center Freiburg - Bad Krozingen
RECRUITINGBad Krozingen, 79189, Germany
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University Medical Center Freiburg, Interdisciplinary Medical Intensive Care
RECRUITINGFreiburg im Breisgau, 79106, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Stick-On patch aims to catch dangerous heart decline sooner
- Heart pump timing put to the test in deadly heart attack shock
- Can Urine-Guided diuretic doses improve heart failure treatment?
- A second chance for the heart: can rehab rewrite the story after shock?
- A sticky patch could reveal hidden heart rhythm dangers
- Blood filter may calm the deadly inflammation of cardiogenic shock