ANATOMIC STAGE III BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE III BREAST CANCER AJCC V8 explained in plain language.
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Custom-Made vaccine takes on aggressive breast cancer
⭐️ VACCINE ⭐️ Recruiting nowThis early-phase trial is testing a personalized vaccine made from a patient's own tumor, combined with drugs that help the immune system attack cancer cells. The study includes about 18 adults with triple negative breast cancer that has spread or come back. The goal is to see if…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: Emory University • Aim: ⭐️ VACCINE ⭐️
Last updated May 01, 2026 14:19 UTC
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New drug combo aims to outsmart Hard-to-Treat HER2 cancers
Disease control Recruiting nowThis early-phase trial tests whether adding pidnarulex to the targeted therapy trastuzumab deruxtecan is safe and effective for people with advanced HER2-positive breast cancer or other solid tumors that have spread or can't be removed. About 36 adults whose cancer has stopped re…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 01, 2026 14:34 UTC
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New study tests metformin to stop diabetes in breast cancer survivors
Disease control Recruiting nowThis study looks at whether the diabetes drug metformin can help prevent or reverse insulin resistance (a step toward diabetes) in women who have finished chemotherapy for early-stage breast cancer. About 200 women will be randomly assigned to receive either metformin plus standa…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 01, 2026 14:32 UTC
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Electric field device joins drug combo to fight advanced cancers
Disease control Recruiting nowThis early-phase study tests a wearable device that creates electric fields (tumor treating fields) combined with either cabozantinib or a chemo-immunotherapy pair (nab-paclitaxel and atezolizumab) in people with advanced solid tumors in the abdomen or chest. The goal is to see i…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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5-Day radiation blast could replace weeks of treatment for breast cancer
Disease control Recruiting nowThis study tests a new, shorter radiation schedule for women with stage I-III breast cancer who have had a lumpectomy. Instead of weeks of daily radiation, patients receive 5 ultra-short treatments that target the whole breast and the surgical cavity at the same time. The goal is…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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New drug cocktail aims to shrink Hard-to-Treat tumors
Disease control Recruiting nowThis early-phase trial tests the safety and best dose of two drugs—ZEN003694 and abemaciclib—given together to people with advanced breast cancer, NUT carcinoma, or other solid tumors that have spread or can't be removed by surgery. The goal is to see if the combination can shrin…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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Custom-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors. The goal is to see if this combination is safe and helps the immune system attack cancer more effectively. …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 29, 2026 15:15 UTC
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New combo attack on tough breast cancer shows promise in early trial
Disease control Recruiting nowThis study tests whether combining tamoxifen with a special form of chemotherapy (liposomal doxorubicin) can shrink or control advanced triple negative breast cancer that has spread. It includes 30 adults whose cancer has not responded to at least two prior treatments. The goal i…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Apr 29, 2026 15:15 UTC
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New hope for hard-to-treat breast cancer: drug combo targets resistance
Disease control Recruiting nowThis study tests whether adding another drug (cediranib or AZD6738) to the PARP inhibitor olaparib can shrink tumors or slow cancer growth in people with advanced BRCA-mutated breast cancer that has stopped responding to PARP inhibitors. About 60 adults with HER2-negative, BRCA-p…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC
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New triple-drug attack shows promise against hard-to-treat breast cancer
Disease control Recruiting nowThis early-phase trial tests whether adding an experimental drug (ZEN003694) to standard chemotherapy and immunotherapy is safe and can shrink tumors in people with advanced triple-negative breast cancer. About 57 participants will receive the combination. The goal is to find the…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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New ultrasound test may predict chemo success early in breast cancer
Diagnosis Recruiting nowThis study tests a new ultrasound technique that uses a contrast dye to measure pressure inside breast tumors. The goal is to see if it can predict how well chemotherapy is working early in treatment. 200 women with locally advanced breast cancer will be scanned before and during…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: Kibo Nam • Aim: Diagnosis
Last updated May 01, 2026 14:33 UTC
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New surgery before lymph node removal may prevent painful arm swelling
Prevention Recruiting nowThis study tests if a procedure called lymphovenous bypass, done before lymph node surgery, can prevent lymphedema (arm swelling) in people with breast cancer or melanoma. The bypass creates a new path for lymph fluid to drain away from the arm. Researchers will compare swelling …
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated May 01, 2026 14:33 UTC
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Brain food: diet trial targets chemobrain in breast cancer patients
Symptom relief Recruiting nowThis study tests whether a 12-week MIND diet program can ease memory problems, fatigue, and mood issues in women with stage II-III triple-negative breast cancer undergoing chemotherapy. About 60 participants will be randomly assigned to either the MIND diet or general health coac…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 01, 2026 14:33 UTC
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Potato power: could a simple starch beat cancer drug joint pain?
Symptom relief Recruiting nowThis study tests if a dietary supplement called resistant potato starch can prevent joint pain and stiffness caused by aromatase inhibitors, a common breast cancer treatment. About 20 women with early-stage breast cancer or at high risk will take the starch alongside their hormon…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Symptom relief
Last updated May 01, 2026 14:32 UTC
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Can a Hair-Growing drug fix Chemo-Free hair loss?
Symptom relief Recruiting nowThis study tests whether minoxidil (the active ingredient in Rogaine) can help with hair loss caused by hormone therapy in breast cancer patients. About 50 women with stage I-IV breast cancer who are on hormone therapy and have noticed hair thinning will either take minoxidil pil…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 01, 2026 14:21 UTC
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New program aims to boost well-being in seniors after breast cancer
Symptom relief Recruiting nowThis study tests a special geriatric care program for people 65 and older who have finished treatment for early-stage breast cancer. The program includes a full health check and follow-up visits to help reduce health problems and improve quality of life. Researchers hope this app…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 01, 2026 14:20 UTC
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Laser therapy offers hope for breast cancer Survivors' vaginal dryness
Symptom relief Recruiting nowThis study tests a laser treatment for vaginal dryness in breast cancer survivors. Many survivors experience dryness due to cancer treatments like chemotherapy or hormone therapy. The study will compare the laser to no treatment in 250 women to see if it reduces symptoms and impr…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated Apr 30, 2026 15:52 UTC
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Stress relief trial aims to ease triple negative breast cancer journey
Symptom relief Recruiting nowThis study tests whether a 10-week stress reduction program is practical and helpful for women with triple negative breast cancer. The program teaches relaxation, coping skills, and communication, and also connects participants with social services for needs like transportation o…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Apr 30, 2026 15:50 UTC
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New study aims to boost Self-Esteem in breast cancer survivors by improving skin health
Symptom relief Recruiting nowThis study tests whether a skin care program can improve skin quality and self-esteem in 25 breast cancer survivors who are starting aromatase inhibitor therapy. Participants will have their skin measured with special imaging and photography. The goal is to ease skin-related side…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Apr 29, 2026 15:02 UTC
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Researchers probe immune secrets of anti-HER2 therapy
Knowledge-focused Recruiting nowThis study collects blood and tumor samples from 230 adults with HER2-positive breast cancer (stages I–IV) who are about to start anti-HER2 drugs like trastuzumab. The goal is to learn how the immune system reacts to these treatments, which may help improve future therapies. Part…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 01, 2026 14:32 UTC
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New tool aims to help women with breast cancer make tough surgery choices
Knowledge-focused Recruiting nowThis study tests a decision-making tool for women newly diagnosed with early-stage breast cancer who are considering whether to also remove the healthy breast as a preventive measure. The tool is designed to provide clear, balanced information to help patients feel more confident…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 01, 2026 14:19 UTC
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Can a PET scan predict breast cancer drug success?
Knowledge-focused Recruiting nowThis study tests whether a special PET scan can predict if a drug combination (abemaciclib plus hormone therapy) will work for people with advanced hormone receptor-positive, HER2-negative breast cancer. About 60 participants will get the treatment and have scans to see if the im…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:48 UTC
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Gene test may predict breast cancer drug success
Knowledge-focused Recruiting nowThis study is for postmenopausal women with early-stage, hormone-sensitive breast cancer. It tests whether a specific gene change (HSD3B1) affects how well the drug letrozole works before surgery. The goal is to learn why some tumors respond better than others, which could help p…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE4 • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:48 UTC
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Breast cancer Survivors' blood samples fuel future research
Knowledge-focused Recruiting nowThis study collects blood samples and health information from 1,300 women who have had stage I-III breast cancer and finished active treatment. The goal is to create a biorepository—a stored collection of samples and data—that scientists can use in future studies to better unders…
Matched conditions: ANATOMIC STAGE III BREAST CANCER AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC