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Breast cancer survivors: could a common diabetes drug lower your risk?

NCT ID NCT06763328

First seen Jan 31, 2026 · Last updated Jun 17, 2026 · Updated 17 times

Summary

This study looks at whether metformin, a diabetes drug, can help prevent or reverse insulin resistance in women who finished chemotherapy for early-stage breast cancer. Insulin resistance raises the risk of diabetes and heart disease, and may also be linked to more aggressive breast cancer. About 80 women will either get metformin plus standard diet and exercise advice, or standard advice alone, and researchers will track their blood sugar levels over two years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UC San Diego Moores Cancer Center

    NOT_YET_RECRUITING

    La Jolla, California, 92093, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California-Riverside

    NOT_YET_RECRUITING

    Riverside, California, 92521, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

breast cancer invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.