ANATOMIC STAGE II BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE II BREAST CANCER AJCC V8 explained in plain language.
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Custom-Made vaccine takes on tough breast cancer
⭐️ VACCINE ⭐️ Recruiting nowThis early-stage study tests a personalized vaccine made from a patient's own tumor, combined with immunotherapy drugs, for triple negative breast cancer. The goal is to see if the vaccine is safe and can help the immune system attack cancer cells. About 18 adults with various st…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: Emory University • Aim: ⭐️ VACCINE ⭐️
Last updated May 26, 2026 06:08 UTC
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New drug combo shows promise in shrinking aggressive breast tumors
Disease control Recruiting nowThis study tests whether adding the drug darolutamide to standard chemotherapy and immunotherapy before surgery can shrink tumors more effectively in people with early-stage androgen receptor positive triple-negative breast cancer. About 51 participants will receive either standa…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Vandana Abramson • Aim: Disease control
Last updated May 26, 2026 06:08 UTC
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5-Day radiation for breast cancer: a game changer?
Disease control Recruiting nowThis study tests a new, shorter radiation treatment for women with stage I-III breast cancer who have had a lumpectomy. Instead of weeks of daily radiation, patients receive 5 ultra-high-dose treatments to the whole breast and surgical area at once. The goal is to see if this app…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 06:07 UTC
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New vaccine combo aims to supercharge immune attack on breast cancer
Disease control Recruiting nowThis study tests whether adding a vaccine called WOKVAC to standard chemotherapy and HER2-targeted therapy before surgery can boost the immune system to kill more breast cancer cells. About 25 adults with early-stage HER2-positive breast cancer will receive the vaccine alongside …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated May 26, 2026 06:04 UTC
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Breast cancer survivors: could a common diabetes drug protect your heart?
Disease control Recruiting nowThis study looks at whether metformin, a common diabetes medicine, can help prevent or reverse insulin resistance (a step toward diabetes) in women who finished chemotherapy for early-stage breast cancer. About 200 women will either get metformin plus standard diet and exercise a…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 06:04 UTC
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Could 6 months of therapy be enough for some breast cancer patients?
Disease control Recruiting nowThis study looks at whether people with early-stage HER2-positive breast cancer who had a complete response to initial chemotherapy can safely stop targeted therapy after 6 months instead of the usual 12. About 1,500 participants will be randomly assigned to either 6 or 12 months…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 26, 2026 06:04 UTC
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New study aims to help latina breast cancer survivors lose weight and improve survival
Disease control Recruiting nowThis study tests two remote weight loss programs designed for Latina breast cancer survivors. The goal is to help participants lose weight and improve their long-term health. The study will enroll 640 women who have had breast cancer in the past 5 years and currently have no sign…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 26, 2026 06:01 UTC
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Shorter radiation before or after breast surgery may cut side effects
Disease control Recruiting nowThis study compares giving a shorter, higher-dose radiation schedule (hypofractionated radiotherapy) either before or after breast cancer surgery. The goal is to see which timing is safer and works better for different types of non-metastatic breast cancer. About 120 adults with …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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Immunotherapy boost may stop High-Risk breast cancer return
Disease control Recruiting nowThis study tests whether adding an immunotherapy drug (durvalumab) to standard chemotherapy can prevent breast cancer from coming back in people with a high-risk form of hormone receptor-positive, HER2-negative breast cancer. About 3,680 adults with stage II or III breast cancer …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Could a shorter, safer chemo regimen beat standard care for aggressive breast cancer?
Disease control Recruiting nowThis study compares a shorter chemotherapy-immunotherapy combination without anthracyclines to the usual treatment for early-stage triple-negative breast cancer. About 2,400 participants will receive either the experimental shorter regimen or standard care. The goal is to see if …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New study tests cheaper drug for ovarian suppression in breast cancer
Disease control Recruiting nowThis study compares two drugs, leuprolide and goserelin, to see how well they lower estrogen in premenopausal women with breast cancer. Both drugs stop the ovaries from making estrogen, which can fuel cancer growth. The trial will test if leuprolide works as well as goserelin. Ab…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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BREAST CANCER BREAKTHROUGH: could less treatment be just as effective?
Disease control Recruiting nowThis study is for people with early-stage triple-negative breast cancer who had a complete response (no cancer left) after chemotherapy plus the immunotherapy drug pembrolizumab. The trial compares receiving more pembrolizumab versus simply being watched (observation) to see if t…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 04, 2026 16:22 UTC
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Potato power: could a simple starch stop cancer drug joint pain?
Symptom relief Recruiting nowThis study tests whether a dietary supplement called resistant potato starch can help prevent joint pain and stiffness caused by aromatase inhibitors, a common breast cancer treatment. About 20 people with early-stage breast cancer or at high risk for it will take the starch dail…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 06:09 UTC
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Brain food: could a special diet beat chemobrain?
Symptom relief Recruiting nowThis study looks at whether a healthy eating plan called the MIND diet can reduce memory and thinking problems (chemobrain) and other symptoms like fatigue and anxiety in women with stage II-III triple-negative breast cancer during chemotherapy. About 60 women will be randomly as…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 06:09 UTC
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Can better skin boost confidence in breast cancer survivors?
Symptom relief Recruiting nowThis study looks at how skin quality and self-esteem change in breast cancer survivors who are starting a type of hormone therapy called aromatase inhibitors. About 35 women with early-stage breast cancer will join. Researchers will use special imaging to track skin changes and s…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 26, 2026 06:08 UTC
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Gentler chemo for seniors: DOROTHY trial aims to cut side effects
Symptom relief Recruiting nowThis study looks at whether a lower dose of the chemotherapy drugs docetaxel and cyclophosphamide can effectively treat early-stage breast cancer in women aged 65 and older. Standard doses often cause harsh side effects in older patients. The goal is to find a dose that works wel…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated May 26, 2026 06:07 UTC
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Can a Hair-Growing drug fix Chemo-Free hair loss?
Symptom relief Recruiting nowThis study tests whether minoxidil (a hair-growth drug) can reduce hair loss caused by hormone therapy in breast cancer patients. About 50 women with stages I-IV breast cancer who are on hormone therapy and have noticed hair thinning will take either a pill or apply a solution da…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 06:00 UTC
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Stress relief trial for aggressive breast cancer launches
Symptom relief Recruiting nowThis study tests whether a 10-week stress reduction program is practical and helpful for people with triple negative breast cancer. The program teaches relaxation, coping skills, and communication, and also connects participants with social services for needs like transportation …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 06:00 UTC
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Needles vs. pain: new study aims to keep black women on lifesaving breast cancer meds
Symptom relief Recruiting nowThis study tests whether in-person acupuncture or virtual acupressure can prevent the joint pain that often causes Black women to stop taking their breast cancer hormone therapy. About 150 Non-Hispanic Black postmenopausal women with early-stage breast cancer will be enrolled. Th…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Emory University • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Laser treatment offers hope for breast cancer survivors suffering from vaginal dryness
Symptom relief Recruiting nowThis study tests a vaginal laser treatment for breast cancer survivors who have vaginal dryness, often caused by cancer treatments like chemotherapy or hormone therapy. About 250 women who finished their main cancer treatment at least a year ago will receive either the laser or a…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated May 18, 2026 11:59 UTC
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New tool aims to ease tough breast cancer surgery decisions
Knowledge-focused Recruiting nowThis study is testing a decision-making tool for women newly diagnosed with early-stage breast cancer. The tool helps them weigh the option of removing the healthy breast as a preventive measure. Researchers want to see if the tool is clear, balanced, and reduces confusion when m…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 06:09 UTC
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Gene test could predict breast cancer drug success
Knowledge-focused Recruiting nowThis study looks at how a specific gene change (HSD3B1) affects the way postmenopausal women with early-stage, hormone-sensitive breast cancer respond to the drug letrozole before surgery. Researchers will measure changes in tumor markers to see if the gene variant makes the drug…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE4 • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated May 26, 2026 06:06 UTC
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New ultrasound marker could make breast cancer surgery more precise
Knowledge-focused Recruiting nowThis early-stage study tests a new type of marker that shows up better on ultrasound for people with breast cancer that has spread to lymph nodes. The marker is placed in the lymph node to help doctors find and remove the right node during surgery. The goal is to see if this mark…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 06:00 UTC
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Breast cancer and sleepless nights: new study investigates the link
Knowledge-focused Recruiting nowThis study looks at how sleep changes in women with early-stage breast cancer during treatment. Researchers will track sleep patterns and quality in 100 participants before, during, and after chemotherapy or radiation. The goal is to understand why sleep problems happen and how s…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:37 UTC
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Researchers track immune cells in HER2 breast cancer patients
Knowledge-focused Recruiting nowThis study looks at blood and tumor samples from 230 adults with HER2-positive breast cancer (stages I-IV) who are starting anti-HER2 drugs like trastuzumab. The goal is to learn how the immune system reacts to these treatments. No new therapy is being tested; instead, researcher…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Breast cancer survivors needed for biobank study
Knowledge-focused Recruiting nowThis study collects blood samples and health information from 1,300 women who have had stage I-III breast cancer and finished active treatment. The goal is to create a biorepository for future research into how individual factors affect long-term cancer outcomes. Participants wil…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated May 18, 2026 12:08 UTC
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Can your social life help you beat Cancer's aftermath?
Knowledge-focused Recruiting nowThis study follows 250 young adults (ages 18-39) recently diagnosed with cancer to see how their social relationships and physical activity change over time and affect their quality of life. Researchers will track hospitalizations, treatment details, exercise habits, and well-bei…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated May 18, 2026 11:59 UTC
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Gut bacteria linked to chemo side effects?
Knowledge-focused Recruiting nowThis study looks at whether changes in gut bacteria are connected to fatigue and nausea in women receiving chemotherapy for early-stage breast cancer. Researchers will collect stool samples and questionnaires from 70 participants before and after treatment. The goal is to better …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 04, 2026 16:23 UTC