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Gene test could predict breast cancer drug success

NCT ID NCT05183828

First seen Jan 26, 2026 · Last updated May 23, 2026 · Updated 18 times

Summary

This study looks at how a specific gene change (HSD3B1) affects the way postmenopausal women with early-stage, hormone-sensitive breast cancer respond to the drug letrozole before surgery. Researchers will measure changes in tumor markers to see if the gene variant makes the drug less effective. The goal is to better understand who benefits most from this treatment, not to provide a new therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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