ACUTE KIDNEY INJURY

This study looked at 18 ICU patients on both a heart-lung bypass machine (ECMO) and a kidney replacement therapy machine. Researchers tested whether adding a special blood thinner (citrate) to the kidney machine could prevent clotting better than standard care. The goal was to ke…

This study tested a new way to monitor kidney oxygen levels during liver surgery to try to prevent acute kidney injury (AKI). 80 adults having liver surgery were randomly assigned to either standard care or extra monitoring that triggered a step-by-step treatment plan if oxygen l…

This study looked at 400 critically ill patients with septic shock and acute kidney injury who needed dialysis. Researchers compared those who used a special filter called Oxiris, which removes toxins and inflammation, to those who used standard filters. The goal was to see if th…

This study tested whether giving the acid-reducing drug pantoprazole during heart surgery could help prevent acute kidney injury. About 100 adults at moderate-to-high risk for kidney damage after surgery took part. Researchers compared pantoprazole to another acid reducer, famoti…

This study tested whether stopping a common blood pressure medicine (Ramipril) before a heart artery scan reduces the risk of kidney damage from the dye used. 44 adults were randomly assigned to either stop the medicine 2 days before the scan or keep taking it. Researchers measur…

This study tested whether giving nitric oxide gas during surgery could lower the chance of acute kidney injury in people having emergency repair of a torn aorta (type A aortic dissection). 106 adults took part. The main goal was to see if fewer patients developed kidney problems …

This study looked at 60 critically ill patients with acute kidney injury and shock who needed dialysis. Researchers compared a special dialysis method that adjusts salt levels (sodium profiling) to standard dialysis. The goal was to see if the special method helps keep blood pres…

This study aims to create a new scoring system to detect acute kidney injury (AKI) early after heart surgery. AKI is a common and serious complication that can lead to longer hospital stays, chronic kidney disease, or even death. Researchers will combine blood and urine tests wit…

This study tested whether quickly removing a small amount of fluid during dialysis can help predict if a patient needs more fluids. Twenty critically ill adults with acute kidney injury on continuous dialysis took part. Researchers compared two speeds of fluid removal to a standa…

This study tested whether giving nitric oxide during heart-lung bypass surgery could prevent acute kidney injury in 250 adults at high risk due to blood vessel problems. Participants received either nitric oxide or a placebo during surgery. The goal was to see if the treatment re…

This study tested whether two forms of activated vitamin D (calcifediol and calcitriol) could prevent or lessen acute kidney injury in critically ill patients. Researchers enrolled 150 adults in the ICU who were at high risk for kidney damage. The goal was to see if these vitamin…

This study tested whether methylene blue, a medicine that affects blood vessel tone, can prevent low blood pressure during kidney dialysis in critically ill patients. 261 adults with acute kidney injury and low blood pressure or requiring blood pressure support took part. The goa…

This study looked at whether a heart ultrasound (echocardiography) can help doctors better manage cirrhosis patients who also develop sudden kidney injury. The goal was to see if heart function measurements could predict which patients would not tolerate fluid replacement therapy…

This study tested a computer system that alerts pharmacists when hospitalized patients are at high risk for kidney injury caused by medications. The pharmacists then worked with doctors to adjust treatments. The goal was to see if this approach could reduce serious kidney complic…

This study aimed to create a tool that helps doctors decide which patients with severe acute kidney injury (AKI) would benefit from seeing a kidney specialist (nephrologist) after leaving the hospital. Researchers looked at 319 patients who needed dialysis for severe AKI to find …

This study looked at 76 adults in intensive care who needed a lung machine (ECMO) for severe pneumonia. Researchers checked if giving the lungs rest by reducing ventilator support changed how well the kidneys worked. They used already-collected medical data, so patients didn't ne…

This study tested whether a computer model could predict kidney damage caused by platinum-based chemotherapy better than doctors. Researchers tracked 77 cancer patients in Taiwan, collecting health data before and after treatment. The goal was to see if the machine learning model…

This study looked at 220 adults with acute kidney injury who needed dialysis. Researchers compared a conservative (less frequent) dialysis approach to the usual thrice-weekly schedule to see if it helped kidneys recover faster. The goal was to learn how to best guide dialysis to …

This study looked at over 5,000 critically ill children from around the world to better understand acute kidney injury (AKI). The goal was to learn how common AKI is, what puts children at risk, and how to predict severe cases. Researchers tested a new scoring system called "rena…

This study tested whether using ultrasound to check fluid tolerance can help doctors manage intravenous fluids better in hospitalized adults with acute kidney injury. 80 participants were randomly assigned to either usual care or care guided by ultrasound results. The main goal w…

This study looked at 35 adults having nose surgeries like rhinoplasty or sinus surgery. Doctors often lower blood pressure during these surgeries to reduce bleeding. The study used special blood tests (NGAL and cystatin C) to check for early, hidden kidney injury that standard te…

This study looked at whether taking ibuprofen before exercising in hot weather can increase signs of kidney injury. Twelve physically active adults ran for an hour in 35°C heat after taking either ibuprofen or a placebo. Researchers measured kidney damage markers in their blood a…

This study examined how gabapentin, a common pain reliever, affects kidney function in 90 obese adults after laparoscopic sleeve gastrectomy. Researchers measured two kidney injury markers (NGAL and DKK3) in the blood and urine. The goal was to see if gabapentin is a safe alterna…

This study involved 20 adults newly diagnosed with multiple myeloma who were starting treatment with daratumumab. Researchers collected blood and urine samples before and 30 days after starting therapy to measure specific biomarkers that might signal early kidney injury. The goal…

This study looked at how very hard exercise temporarily affects kidney function in 40 active adults. Researchers used sensitive urine tests to detect early signs of kidney stress that standard blood tests might miss. The goal was to better understand the short-term, reversible ch…

This study looked at 455 adults who had heart surgery with a heart-lung machine. Researchers checked if routine blood tests and kidney function before surgery could predict acute kidney injury afterward. The goal is to help doctors identify high-risk patients earlier.

This study looked at whether giving antibiotics before a kidney tube placement (to drain urine blocked by a tumor) prevents urinary tract infections. Researchers reviewed records of 320 cancer patients who had this procedure. The goal was to see if antibiotics made a difference i…

This study tested whether a lab-based prediction model can accurately forecast acute kidney injury after cardiac surgery. Researchers analyzed data from 2500 adult patients to validate the Demijirian scale and compare it with other prediction tools. The goal is to identify kidney…

This study looked at whether a protein called vasorin can help predict kidney injury and death in people with septic shock. Researchers measured vasorin levels in 50 intensive care patients. The goal was to see if higher vasorin levels are linked to worse outcomes, which could le…

This study reviewed medical records of 238 severely burned adults who needed continuous kidney therapy (CRRT) in the intensive care unit. Researchers looked at how the timing of starting therapy and the severity of kidney injury related to survival and hospital stay. The goal was…

This study looked at 174 older adults (ages 65-80) having lumbar fusion surgery to see if one type of IV fluid (sodium acetate Ringer's) protects the kidneys better than another (sodium lactate Ringer's). Researchers measured kidney injury markers in urine and blood after surgery…

This study tested a new way to send alerts to doctors when a patient develops acute kidney injury (AKI). Instead of alerting for every case, researchers used a computer model to identify which patients would benefit most from the warning. Over 2,000 adults with AKI took part. The…

This study aimed to find better ways to predict kidney injury after heart surgery. Researchers tested new biomarkers in over 3,000 patients who developed kidney problems within two days of surgery. The goal was to see if these tests could identify which patients would get worse o…

This study looked at how COVID-19 causes organ failure in intensive care patients. Researchers tracked 380 adults with suspected or confirmed COVID-19 in the ICU, measuring kidney injury, breathing problems, and survival rates. The goal was to better understand the disease, not t…