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Massive global study maps kidney injury in sick kids

NCT ID NCT01987921

Knowledge-focused Sponsor: Children's Hospital Medical Center, Cincinnati Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at over 5,000 critically ill children from hospitals worldwide to learn more about acute kidney injury (AKI). The goal was to better understand how common AKI is, what puts children at risk, and how to predict it using a tool called 'renal angina.' The study did not test a new treatment but aimed to improve diagnosis and future care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

5,237 people

The number who actually took part.

Start date

Jan 2014

Finished

Dec 2014

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All medical and surgical patients admitted to the pediatric intensive care unit

Ages

3 months to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age greater than 90 days * Age less than 25 years Exclusion Criteria: * Patients on maintenance hemodialysis, peritoneal dialysis, or with chronic kidney disease with a baseline eGFR of \<15 mL/min/1.73m2 * Patients with renal transplant received less than 90 days from the ICU admission. * Patients admitted to ICU immediately post-operative to within three months following surgical correction of congenital heart disease. * Patients with uncorrected congenital heart disease. This criteria does not include patients with isolated uncorrected ventricular septal defect (VSD), atrial septal defect (ASD), patent ductus arteriosus (PDA) and patent foramen ovale (PFO). * Patients following cardiac catheterization.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury

Contacts and locations

Locations

  • Children's Hospital Colorado

    Aurora, Colorado, United States

  • Children's Hospital at Westmead

    Westmead, New South Wales, Australia

  • Children's Mercy Hospitals and Clinics

    Kansas City, Missouri, 64108, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Cohen Children's Medical Center of NY

    New Hyde Park, New York, 11354, United States

  • Dept of Child Health Airlangga University/Dr. Soetomo Hospital

    Surabaya, Indonesia

  • Dept of Child Health Cipto Mangunkusumo/University of Indonesia

    Jakarta, Indonesia

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Helen DeVos Children's Hospital

    Grand Rapids, Michigan, 49503, United States

  • King's College Hospital

    London, WC2R 2LS, United Kingdom

  • Montreal Children's/McGill

    Montreal, QC H3H 1P3, Canada

  • Mother and Child Health Care

    Belgrade, Serbia

  • Nanjing Children's Hospital

    Nanjing, China

  • Nemours/Alfred I. duPont Hospital for Children

    Wilmington, Delaware, 19803, United States

  • Ospedale Pediatrico Bambino Gesu

    Rome, 00165, Italy

  • Seoul National University Children's Hospital

    Seoul, South Korea

  • Stanford University

    Palo Alto, California, 94305, United States

  • Stony Brook Long Island Children's Hospital

    Stony Brook, New York, 11794, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • The Sydney Children's Hospitals Network

    Sydney, NSW 2031, Australia

  • University Children's Hospital

    Belgrade, Serbia

  • University Children's Medical Institute, National University Hospital

    Singapore, Singapore

  • University of Alabama

    Birmingham, Alabama, 35203, United States

  • University of British Columbia and Children's and Women's Health Center of British Columbia Branch

    Vancouver, Canada

  • University of Edmonton

    Edmonton, AB T6G 2R3, Canada

  • University of Iowa

    Des Moines, Iowa, 52242, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of New Mexico

    Albuquerque, New Mexico, 87131, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23284, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63130, United States

  • Yale University

    New Haven, Connecticut, 06510, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.