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Can ultrasound prevent fluid overload in kidney patients?

NCT ID NCT06411080

Knowledge-focused Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether using ultrasound to check fluid tolerance is feasible in hospitalized patients with acute kidney injury (AKI). 80 non-ICU adults were randomly assigned to receive either standard care or an ultrasound-guided fluid assessment. The main goal was to see if doctors could follow the ultrasound protocol. Secondary goals looked at fluid amounts, diuretic use, and kidney function changes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Point-of-care ultrasound (POCUS) for fluid tolerance assessment
What this could lead to
If successful, this approach could help doctors give fluids more safely to kidney injury patients, potentially reducing complications.
What could go wrong
This is a small pilot study focused on feasibility, not on proving better outcomes. The results may not change practice without larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Oct 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults ≥ 18 year-old 2. Admitted to the hospital 3. Acute kidney injury defined by the KDIGO criteria\[48\] 4. Fluid expansion is considered by attending nephrologist or already ongoing Exclusion Criteria: 1. Admitted to the intensive care unit 2. Known stage 5 chronic kidney disease according to the KDIGO classification receiving renal replacement therapy or not. 3. Renal replacement therapy for AKI has been initiated or is planned within 24 hours

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury

Contacts and locations

Locations

  • Centre Hospitalier de l'Université de Montréal

    Montreal, Quebec, H2X 3H8, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.