Burn

Researchers are studying how the antibiotic ertapenem behaves in patients with severe burns who are on breathing machines. The trial measures drug levels in the blood after two intravenous doses to see how the body processes the medicine. They also check whether a standard 1-gram…

This study tests a new lab-grown skin substitute (EHSG-KF) for treating deep burns in adults and teens. It compares the substitute to standard skin grafts to see if it covers wounds better and is safer. The goal is to improve healing and reduce the need for large skin donations f…

This study tested whether a cream called Nefopam can prevent or reduce scarring in burn patients. Fifty adult burn patients had small, controlled scratches made on their hips. One scratch was treated with the Nefopam cream and the other with a placebo cream. Researchers measured …

This trial investigates whether high-dose vitamin E (alpha-tocopherol) can reduce oxidative stress and improve outcomes in adults with severe burns covering at least 40% of their body. Participants receive vitamin E drops after surgery, and researchers measure vitamin levels, lun…

This study tested whether adding albumin (a protein) to standard IV fluids helps adults with severe burns covering at least 25% of their body. 101 participants were randomly assigned to receive either standard fluids alone or standard fluids plus albumin during the first 24-48 ho…

This study tested a device that automatically adjusts oxygen levels for hospitalized patients with serious injuries or illnesses. 300 adults received either the automated device or standard manual oxygen adjustments. The goal was to see if the device kept oxygen levels in a safer…

This study tested whether fresh frozen plasma (FFP) works better than albumin for fluid replacement in adults with severe burns covering over 20% of their body. Fifty-nine participants were randomly assigned to receive either FFP or albumin within 8 hours of injury. The goal was …

Researchers at Mansoura University are testing whether two blood markers, procalcitonin and highly sensitive C-reactive protein, can detect sepsis early in people with major burns. The study will enroll 30 patients aged 3 to 65 with second or third degree burns. Blood samples are…

This study tested a new, low-cost tool called the Intensive Care Infection Score (ICIS) to see if it can better detect bacterial infections in burn patients compared to standard blood tests. Researchers studied 97 adults and children hospitalized for burns. The goal was to improv…

This trial tests whether a mobile app can improve burn prevention and first aid knowledge among families living in tent cities and container houses after an earthquake. Sixty families will be randomly assigned to either receive standard training plus the app or standard training …

This study compared a serious digital game to a traditional lecture for teaching burn prevention and first aid to 44 students. Participants took a knowledge test before and after the lesson, and again two weeks later. The goal was to see which method helped students learn and rem…

This pilot study tested whether giving vitamin D shortly after a burn injury could prevent chronic pain. Forty adults with burns took either vitamin D or a placebo and were followed for six months. Researchers also studied how vitamin D affects the immune system after a burn. The…

This trial tests whether replacing part of a standard rehabilitation session with Wii Fit or Pilates exercises improves walking, balance, and leg strength in adults with healed lower-limb burns. Participants receive 60-minute supervised sessions three times a week for 12 weeks, s…

This study tests a new two-sided pad (Debrisoft Duo) for cleaning wounds by removing dead tissue. About 104 adults with various wound types (like diabetic ulcers or burns) will be randomly assigned to the new pad or the current one-sided pad. The main goal is to see if the new pa…

This study tests whether watching a custom 360-degree virtual reality video during dressing changes can lower pain, anxiety, and the need for opioid painkillers in adults recovering from burn surgery. Eighty participants will wear VR headsets while their bandages are changed and …

This pilot study tests whether a technique called conditioning with open-label placebo (COLP) can help patients with spinal cord injuries, polytrauma, or burns reduce their opioid painkiller doses without losing pain relief. Participants receive a sugar pill and an essential oil …

This study tested whether playing virtual reality games could help people with arm burns recover movement and reduce fear of using their injured arm. 150 adults with upper limb burns took part. The approach used fun, interactive exercises to improve walking and arm function.

This study is testing a pad used to clean wounds, such as diabetic ulcers, leg ulcers, pressure sores, surgical wounds, and burns. The goal is to see if the pad safely removes debris and improves the wound bed right after use. About 184 adults with these types of wounds will take…

This study tested whether adding whole-body vibration training to standard physical therapy helps children aged 10-16 recover from severe burns on their legs and trunk. 60 children participated, half receiving vibration therapy plus exercise, and half receiving exercise alone. Th…

This study tested whether adding traditional Chinese medicine (TCM) — like herbs, acupuncture, and massage — to standard care helps people with mild to moderate burns recover faster. Twenty adults received either TCM plus usual care or usual care alone. Researchers measured pain,…

This study tested whether a 12-week program of supervised jumping and plyometric exercises could help children aged 10-18 recover leg strength and power after severe burns. 62 participants were split into two groups: one did the plyometric program, the other did standard exercise…

This study tested whether using bandages printed with cartoon characters helps children feel less fear, stress, and pain during burn dressing changes. 42 children aged 6-11 with second-degree burns were randomly assigned to get either cartoon or plain bandages. The goal was to se…

This study tested whether resistance training with a blood flow restriction (venous occlusion) helps people regain hand strength and function after a burn injury. Thirty-four patients with healed hand burns did either standard rehab or the same exercises with a cuff limiting bloo…

This study tested whether laser treatment or a small punch biopsy (removing a tiny piece of scar tissue) improves burn scars better than no treatment. Seventeen adults with burn scars each had three small areas on one scar treated differently: laser, punch biopsy, or nothing. Res…

This study tested whether a long-acting numbing drug called liposomal bupivacaine (Exparel) can reduce pain and opioid use after skin graft harvesting in burn patients. 74 adults with small burns received either Exparel, lidocaine, or a nerve block. Researchers measured pain scor…

This study looked at whether serial casting (applying a cast that is changed weekly) can improve arm and hand movement in adults who have stiff joints from burn scars. Twelve burn survivors with limited range of motion received one week of usual care, then serial casting if neede…

This study looked at whether different exercise programs could help children aged 10 to 17 who had severe burns on their legs. 84 children were split into three groups: balance training, jump-based (plyometric) training, or a mix of both. They exercised three times a week for eig…

This study tested a 12-week program combining Russian current (a type of electrical stimulation) with muscle energy techniques in 100 adults recovering from circumferential upper arm burns. The goal was to reduce pain, improve muscle strength, and lessen disability. Results showe…

This study tested if shock wave therapy works better than standard physical therapy for improving burn scars on the forearm. 80 adults with partial-thickness burns that had healed for at least six months took part. Researchers measured scar thickness and appearance before, after …

This small pilot study tested a set of mouth tools called the Easy Stretch Toolkit in 8 people with facial burns or other conditions causing facial tightness. The goal was to see if using the tools could improve facial movement and quality of life over 8 weeks. The study measured…

This study tested two treatments—Botox injections and shock wave therapy—to see which works better for improving hand movement and reducing scar severity in children with burn scars on their hands. Sixty children aged 6 to 18 took part, and both treatments were added to a standar…

This study tested whether breathing exercises and using a stress ball during dressing changes can reduce pain, anxiety, and improve comfort in burn patients. 210 adults with burns on 15% or less of their body took part. Researchers measured pain, anxiety, comfort, and vital signs…

This study tested whether using virtual reality (VR) during wound dressing changes can reduce pain and improve sleep in adults with moderate to severe burns. Sixty patients took part, and the researchers compared VR to standard care. The goal was to see if VR could make a painful…

This study looked at whether a higher daily dose of vitamin D (4000 IU) is better than the standard dose (400 IU) for adults who had a major burn injury and are vitamin D deficient. 48 people took part, and researchers measured changes in their physical and mental health, as well…

This study looked at whether using virtual reality glasses or music during burn dressing changes can lower pain, anxiety, and fear of pain. 120 adults with burns on less than 15% of their body took part. Researchers measured their pain and anxiety levels using standard scales.

This study tested whether adding whole-body vibration training to standard physical therapy helps people recovering from deep second-degree burns on their legs. Sixty adults aged 20 to 50 took part. They did standard exercises plus vibration sessions three times a week for 12 wee…

This study tested whether high-flow oxygen therapy works better than standard nasal oxygen for children with burns who need sedation for procedures. Fifty children aged 1 to 14 with moderate to severe burns took part. The goal was to see if high-flow oxygen reduces breathing prob…

This study tested whether kinesiotape, low-level laser therapy, or a combination of both works best for improving burn scars. Sixty people with hypertrophic scars from burns received one of the three treatments for 8 weeks. The goal was to see which approach made scars softer and…

This study tested whether tea tree oil ointment helps heal second-degree burns better than standard dressings. Thirty patients with recent burns covering up to 10% of their body were treated. Researchers looked at wound appearance, infection signs, and healing progress over 10 da…

This trial investigates how the body handles sevoflurane, an inhaled anesthetic used for short-term sedation, in burn patients in the intensive care unit (ICU). It compares drug levels in burn patients with those in other ICU patients to see if dosing needs adjustment. The study …

This study looks back at medical records of over 1,000 people hospitalized for burns to see which of three scoring systems—ABSI, Revised Baux, or Modified Ryan—best predicts whether a patient will survive. The goal is to find the most accurate tool for doctors to use when making …

This study looked at whether spraying water on the skin can help burn survivors keep their body temperature down during exercise in hot conditions. Researchers compared core and skin temperature changes in 31 participants (burn survivors and healthy controls) while they exercised…

This study looked at 85 adults who had a burn injury to understand how fatigue affects their daily activities, quality of life, and ability to return to work. Participants filled out questionnaires 6 and 12 months after their injury. The goal is to identify problems early and imp…

This study tested whether a special 3D X-ray done in the operating room can replace standard CT scans after repairing an abdominal aortic aneurysm. 427 patients were randomly assigned to either the new 3D scan or the usual approach. The goal was to see if the new method reduces r…

This study looked back at the medical records of 465 adults admitted to the ICU for burns. Researchers wanted to see if existing scoring systems can accurately predict which patients are most at risk of dying. The goal is to help doctors make better decisions and improve care for…

This study aimed to find the best dose of the antibiotic ceftazidime for critically ill children with severe burns. Researchers took blood samples from 3 children to measure how the drug moves through the body. The goal was to learn how to personalize dosing to improve treatment …

This completed study from Versailles Hospital looked back at 200 medical reports of adults with skin injuries like cuts, scrapes, burns, and leg ulcers. The goal was to see how well pain was controlled during treatment. Researchers also interviewed some patients and staff to chec…

This study tested whether a therapy called 'illusory movements' (where patients imagine or sense movement without actually moving) could help reduce muscle breakdown in people with severe burns covering 20% or more of their body. Researchers measured energy use, muscle loss, and …

This completed study looked at how the immune system is weakened after septic shock, severe trauma, burns, or major surgery. Researchers took blood samples from 552 patients and healthy volunteers to measure immune function. The goal was to find better ways to predict and manage …

This study looked back at the medical records of 238 severely burned adults who needed continuous kidney therapy (CRRT) in the intensive care unit. The goal was to see how the timing of starting CRRT and the severity of kidney injury related to survival and how long patients stay…