Xuanwu Hospital, Beijing

This trial tests whether giving blood pressure medication inside a mobile stroke unit—a special ambulance with a CT scanner—can improve outcomes for people having a brain bleed. About 706 adults with high blood pressure and a recent stroke will be randomly assigned to either the …

This study tests a non-invasive device that uses gentle electrical stimulation on the brain to see if it can safely lower blood pressure in people with mild hypertension. Sixty adults aged 30-65 with mild high blood pressure will receive either real or sham stimulation for 20 min…

This study tests a new, non-drug treatment for high blood pressure called high-intensity transcranial alternating current stimulation (Hi-tACS). It uses gentle electrical currents on the scalp to stimulate the brain. The trial will include 50 adults with primary hypertension to s…

This study tests a special balloon coated with medicine to open narrowed arteries in the brain and prevent strokes. About 264 people with severe artery narrowing will be treated and followed for 12 months. The goal is to see if the balloon is safe and keeps arteries open better t…

This study tests whether efavirenz, a drug used for HIV, can help people with Creutzfeldt-Jakob disease (CJD) live longer. CJD is a rare, rapidly fatal brain disorder. The trial will enroll 246 adults and randomly assign them to receive either efavirenz or a placebo. The main goa…

This study looks at 518 adults with a severe stroke caused by a blockage in the main artery at the back of the brain. It compares two standard treatments: a procedure to remove the clot (endovascular therapy) versus medication alone. The goal is to see which approach leads to bet…

This study tests a 24-week dietary program for overweight or obese women with polycystic ovary syndrome (PCOS). The goal is to see if a carefully planned, calorie-controlled diet can improve menstrual regularity and metabolic health better than standard care. 160 women will parti…

This pilot study tests whether a non-invasive brain stimulation technique called temporal interference can safely help regulate blood pressure. Researchers will enroll 25 adults with either mild untreated hypertension or hard-to-treat hypertension, as well as people with low bloo…

This large study will test whether giving stroke survivors personalized temperature warnings through a smartphone app can lower their chance of having another stroke. About 5,000 people who recently had an ischemic stroke will be split into two groups: one gets the app alerts and…

This study tests whether a mobile app that sends personalized temperature health warnings and risk management tips can reduce the chance of a second stroke. Over 10,000 people who recently had a stroke will use the app for one year. Researchers will track how many have another st…

This study tests a comprehensive management service package for older adults (65+) who have two or more chronic conditions like high blood pressure, diabetes, or arthritis. The package includes digital tools, personalized lifestyle advice, and long-term support. Researchers will …

This study will test a new radioactive tracer called FBFP in 30 stroke patients and 20 healthy volunteers. The tracer is used with a PET/MR scanner to take detailed pictures of the brain. The goal is to see if FBFP can help doctors diagnose and understand stroke better. Participa…

This study tests an artificial intelligence system designed to automatically score disability after a stroke using the Modified Rankin Scale. Researchers will compare the AI's scores to those from trained clinicians in 490 stroke patients. The goal is to see if the AI can provide…

This study will check if an artificial intelligence (AI) system can accurately score stroke severity as well as a trained doctor. About 297 adults with a recent stroke will have their speech and facial movements recorded. The AI will analyze these recordings to produce a G-FAST s…

This study will test a new intelligent diagnostic system for orthostatic hypotension (a sudden drop in blood pressure when standing up). The system continuously monitors blood pressure, brain blood flow, and heart signals to classify the condition more precisely. Researchers plan…

This study aims to create a more accurate diagnostic system for people with disorders of consciousness, such as coma or vegetative state, after severe brain injury. Researchers will combine clinical exams, brain scans, and electrical brain tests to develop an intelligent tool. Th…

This study tests whether adding a traditional Chinese medicine formula called Bu Yang Huanwu Decoction (in capsule form) to standard treatment can prevent leg pain at rest or foot ulcers in people with diabetic lower extremity vascular disease. About 300 adults aged 18 to 70 with…

This study tests whether a smartphone app that gives personalized tips on managing stroke risk factors can reduce the chance of having another stroke. Over 5,000 people who recently had a mild-to-moderate stroke will use the app for one year. Researchers will track how many have …

This study tests whether taking a daily hot bath (40-42°C for 20 minutes) at home can reduce epileptic seizures in children with CDKL5 deficiency disorder. The trial will include 34 children aged 6 months to 14 years whose seizures are not controlled by medication. Researchers wi…

This study tests whether a 6-week exercise program, added to usual pain medication, can reduce disability and pain in adults aged 60 and older with chronic low-back pain and signs of back muscle degeneration. About 314 participants will be randomly assigned to either the exercise…

This study tests a nasal device (iNAP) that uses gentle suction to keep the airway open during sleep. It includes 65 adults aged 50-75 with mild cognitive impairment and moderate-to-severe sleep apnea. Half will use the device nightly for 24 weeks, while the other half receive sl…

This study tests whether a gentle electrical current applied to the scalp (called tACS) can improve memory and thinking in people with mild Alzheimer's disease. Researchers will compare real stimulation to a sham (fake) version in 160 participants. The goal is to see if this safe…

This early-phase study will test whether shining near-infrared light on the head each day can help people with mild to moderate Alzheimer's disease. Forty participants will receive 30-minute light sessions six times a week for 96 weeks. Researchers will measure changes in thinkin…

This study will measure certain proteins in the blood of people who have had a brain hemorrhage (bleeding in the brain) and compare them to healthy volunteers. The goal is to see if these proteins are linked to inflammation after the bleed. No drugs or treatments are being tested…

This study aims to find out how reliable the DiaMem memory test is when taken multiple times. Researchers will have 30 adults aged 60 or older take memory tests once a day for 6 days. The goal is to see if scores stay consistent, which would help doctors better assess memory prob…

This study looks at whether a new, evidence-based nutrition guideline can improve care for patients in surgical intensive care units (ICUs). About 200 healthcare workers from Chinese hospitals will use the guideline and be checked for how well they follow it. The goal is to see i…

This study will observe how different spinal problems—like scoliosis, stenosis, or herniated discs—change the way people walk and use their back muscles. Researchers will compare 120 older adults (age 60+) with these conditions to healthy volunteers using motion cameras and muscl…

This study will give mild electrical pulses to a brain region called the piriform cortex in 10 people with drug-resistant epilepsy who already have electrodes implanted for seizure monitoring. Researchers will record how the brain responds, aiming to understand which networks are…