Brain zaps reveal hidden epilepsy circuits

NCT ID NCT07305311

Not yet recruiting Knowledge-focused Sponsor: Xuanwu Hospital, Beijing Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will give mild electrical pulses to a brain region called the piriform cortex in 10 people with drug-resistant epilepsy who already have electrodes implanted for seizure monitoring. Researchers will record how the brain responds, aiming to understand which networks are involved in seizures. The goal is not to treat epilepsy now, but to gather knowledge that could lead to better brain-stimulation therapies in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: single-pulse electrical stimulation (SPES) via implanted electrodes
What this could lead to: If successful, this could point toward a new brain-stimulation target to reduce seizures in people with drug-resistant epilepsy.
What could go wrong: This is a very small, early-stage study (10 people) that only observes brain activity—it does not test a treatment. Results may not lead to a therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROMODULATION REFRACTORY EPILEPSY

Contacts and locations

Locations

Xuanwu Hospital

Beijing, Beijing Municipality, 100053, China

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