Brain zaps reveal hidden epilepsy circuits

NCT ID NCT07305311

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will give mild electrical pulses to a brain region called the piriform cortex in 10 people with drug-resistant epilepsy who already have electrodes implanted for seizure monitoring. Researchers will record how the brain responds, aiming to understand which networks are involved in seizures. The goal is not to treat epilepsy now, but to gather knowledge that could lead to better brain-stimulation therapies in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

single-pulse electrical stimulation (SPES) via implanted electrodes

What this could lead to

If successful, this could point toward a new brain-stimulation target to reduce seizures in people with drug-resistant epilepsy.

What could go wrong

This is a very small, early-stage study (10 people) that only observes brain activity—it does not test a treatment. Results may not lead to a therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xuanwu Hospital

    Beijing, Beijing Municipality, 100053, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••