Brain zap study aims to decode OCD's Approach-Avoidance conflict

NCT ID NCT06596447

Recruiting now Knowledge-focused Sponsor: Baylor College of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study will implant deep brain stimulation devices in 10 adults with severe, treatment-resistant OCD to record brain activity during approach and avoidance tasks. Researchers will compare clinic-based and at-home recordings to find neural markers of OCD symptoms. The goal is to better understand how the brain drives compulsive behavior, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Deep brain stimulation (DBS) device
What this could lead to: If successful, this could reveal brain signals that track OCD symptoms, helping doctors adjust DBS therapy more precisely.
What could go wrong: This is a very small early study with only 10 people, focused on understanding the brain rather than testing a new treatment. It may not lead to direct benefits for patients.

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Conditions

The condition(s) this trial relates to.

obsessive-compulsive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROMODULATION OBSESSIVE COMPULSIVE DISORDER (OCD)

Contacts and locations

Locations

Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States

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