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Sound waves to the brain: a new hope for Tough-to-Treat OCD?

NCT ID NCT07704632

Recruiting now Symptom relief Sponsor: Sunnybrook Health Sciences Centre Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study tests whether a special helmet that delivers focused ultrasound can safely and effectively calm overactive brain circuits in people with severe obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments. Participants receive two sessions of this non-invasive brain stimulation, spaced a month apart. The goal is to see if the procedure is safe and if it can reduce OCD symptoms and improve quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
focused ultrasound delivered via the Next Generation Dome Helmet (NGDH) device
What this could lead to
If successful, this could offer a non-invasive, drug-free option to reduce OCD symptoms in people who haven't responded to standard treatments.
What could go wrong
This is an early feasibility study with only 20 participants, so results may not apply broadly. The procedure carries risks like any brain intervention, and symptom improvement is not guaranteed.

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Conditions

The condition(s) this trial relates to.

obsessive-compulsive disorder obsessive-compulsive personality disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBSESSIVE - COMPULSIVE DISORDER OBSESSIVE COMPULSIVE DISORDER (OCD) OCD

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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