Ancient herbal recipe tested to save diabetic legs from ulcers

NCT ID NCT07658807

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a traditional Chinese medicine formula called Bu Yang Huanwu Decoction (in capsule form) to standard treatment can prevent leg pain at rest or foot ulcers in people with diabetic lower extremity vascular disease. About 300 adults aged 18 to 70 with diabetes and early to moderate leg artery disease will be randomly assigned to receive either standard care plus the herbal capsules or standard care alone for 6 months. The main goal is to see if the herbal formula reduces the chance of developing serious leg complications over one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Hua Yu Wan Capsule (a modern preparation of the traditional Chinese medicine formula Bu Yang Huanwu Decoction)
What this could lead to
If it works, this could point toward a new way to prevent serious leg complications in people with diabetes, potentially reducing the need for amputation.
What could go wrong
This is a single Phase 3 trial with 300 participants, so results may not apply to everyone. The herbal formula may not provide additional benefit over standard care, and side effects are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Xuanwu Hospital

    Beijing, China

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