Hot baths tested as seizure treatment for rare childhood disorder

NCT ID NCT07602205

First seen May 23, 2026 · Last updated Jun 20, 2026 · Updated 5 times

Summary

This study tests whether taking a daily hot bath (40-42°C for 20 minutes) at home can reduce epileptic seizures in children with CDKL5 deficiency disorder. The trial will include 34 children aged 6 months to 14 years whose seizures are not controlled by medication. Researchers will measure how many participants have at least a 50% drop in seizure frequency over 12 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hot water baths (40-42°C for 20 minutes daily)

What this could lead to

If it works, this could offer a simple, drug-free way to reduce seizures in children with CDKL5 deficiency disorder.

What could go wrong

This is a very small early trial with only 34 participants. The treatment is unproven, and hot baths may not reduce seizures or could cause discomfort or safety risks.

Conditions

The condition(s) this trial relates to.

developmental and epileptic encephalopathy, 2 epilepsy Fever

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.