Could a simple dural patch boost recovery after spinal cord injury?

NCT ID NCT07733401

Not yet recruiting Disease control Sponsor: Xuanwu Hospital, Beijing Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial tests whether adding a procedure called expansile duraplasty — opening and expanding the tough membrane around the spinal cord — to standard spinal surgery can improve neurological recovery in adults with acute severe spinal cord injury. Participants are randomly assigned to receive either standard surgery alone or standard surgery plus the dural patch. The study tracks motor function, walking ability, independence, and safety over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: expansile duraplasty (a surgical procedure that opens and expands the spinal cord covering to relieve pressure)
What this could lead to: If it works, this could point toward a better surgical approach for severe spinal cord injuries, potentially improving motor recovery and quality of life.
What could go wrong: This is a relatively small, early-stage trial, so results may not apply to all patients. The added surgery carries risks like infection or cerebrospinal fluid leak.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE SPINAL CORD INJURY (SCI) SPINAL CORD INJURY

Contacts and locations

Locations

Beijing Jiangong Hospital

Beijing, Beijing Municipality, China
Beijing Shuili Hospital

Beijing, Beijing Municipality, China
Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine

Cangzhou, Hebei, China
Gaozhou Hospital of Traditional Chinese Medicine, Guangdong Province

Maoming, Guangdong, China
Jinan Central Hospital, Affiliated to Shandong First Medical University

Jinan, Shandong, China
Liaocheng Brain Hospital

Liaocheng, Shandong, China
Shandong University Qilu Hospital (Dezhou Branch)

Dezhou, Shandong, 253001, China
Shanxi Provincial People's Hospital

Taiyuan, Shanxi, China
The First Hospital of Hebei Medical University

Shijiazhuang, Hebei, China
The Third Affiliated Hospital of Southern Medical University

Guangzhou, Guangdong, China
Tianjin Medical University General Hospital

Tianjin, Tianjin Municipality, China
Xuanwu Hospital Inner Mongolia Hospital (Chifeng City Hospital)

Chifeng, Inner Mongolia, China
Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, 100053, China

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