Brain zaps during surgery may ease Post-Op anxiety
NCT ID NCT07713368
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This trial tests whether a mild electrical current applied to the brain during spine tumor surgery can lower anxiety afterward. Adults aged 18 to 65 scheduled for elective intraspinal tumor removal will receive either real or sham stimulation for 20 minutes right after anesthesia. Researchers will track anxiety scores, pain, sleep quality, and recovery for up to three months after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcranial alternating current stimulation (tACS) delivered via a non-invasive device
- What this could lead to
- If it works, this could offer a drug-free way to lower anxiety after spine surgery, helping patients recover faster.
- What could go wrong
- This is a small, early-stage trial, and the effect on anxiety may be minimal or not last. The stimulation is low-intensity and generally safe, but individual responses can vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 102 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Jul 2026
An estimate. Start dates often move.
- Expected to finish
-
Mar 2029
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 65 years old * Scheduled for elective intraspinal tumor resection under general anesthesia * American Society of Anesthesiologists physical status I-III * Able to understand and complete the Hospital Anxiety and Depression Scale and other study-related questionnaires * Voluntarily sign the informed consent form * Right handed Exclusion Criteria: * Preoperative HADS-A score ≥ 8 * History of psychiatric disorders (e.g., depression, psychosis) or use of psychotropic medications within the past 3 months * History of neurological diseases (e.g., epilepsy, stroke, dementia) or severe head trauma * Contraindications to transcranial alternating current stimulation, including metallic implants in the head, skull defects, or a history of seizures * Severe visual or auditory impairment that affects communication * severe cardiovascular and cerebral vascular diseases * Participation in other clinical trials within the past 30 days * A Mini-Mental State Examination (MMSE) score \< 15
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Intraspinal tumor are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Xuanwu Hospital
Beijing, 100053, China