University Of Oxford

This study is testing whether a new experimental rabies vaccine can be safely given at the same time as the standard licensed vaccine. Researchers want to see if this combination creates a strong immune response with fewer clinic visits. The trial will involve 40 healthy adults i…

This study tests whether adding cannabidiol (CBD) to the standard drug clozapine can improve symptoms in people with treatment-resistant psychosis. About 250 participants will receive either CBD or a placebo for 12 weeks, alongside their usual medication. The goal is to see if CB…

This study tests whether adding cannabidiol (CBD) to standard antipsychotic medication can improve symptoms in people experiencing their first episode of psychosis who haven't responded well to initial treatment. About 250 participants aged 16-40 will receive either CBD or a plac…

This study looks at how three malaria drugs (piperaquine, pyronaridine, and artesunate) interact when taken together. It involves 24 healthy adults in Thailand who will receive the drugs in different orders and be monitored for side effects and drug levels. The goal is to underst…

This study will enroll 2000 adults with major depressive disorder or bipolar depression to understand why some people respond to treatment and others do not. Researchers will analyze clinical symptoms, genetics, metabolism, and immune markers. Participants may also be contacted f…

This study looks at whether a special ankle-worn device can track how well toddlers with Duchenne muscular dystrophy (DMD) move during their normal day. Currently, there is no good way to test new medicines in children under 4 with DMD. The study will involve 30 boys with DMD and…

This study looks at how the antidepressant fluoxetine (Prozac) influences decision-making and social skills in healthy young people aged 18 to 24. Participants will take either fluoxetine or a placebo for a week and complete tasks measuring emotion recognition, social sensitivity…

This study looks at why some people with hip impingement (a bony bump causing hip pain) still have pain after doing physiotherapy exercises. Researchers will ask 175 adults about their emotions, fears, and pain types before and after a 4-month rehab program. The goal is to find h…