CBD trial aims to stop psychosis before it starts

NCT ID NCT07434973

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether cannabidiol (CBD), a non-psychoactive cannabis compound, can reduce psychotic symptoms in 586 young people (ages 12-35) at high risk for psychosis. Participants take either CBD or a placebo daily for two years. The goal is to see if CBD can ease symptoms and prevent progression to full psychosis.

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Conditions

The condition(s) this trial relates to.

Psychotic Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Biobizkaia Health Research Institute (Asociación Instituto de Investigación Sanitaria)

    Bilbao, Spain

  • Cambridgeshire and Peterborough NHS Foundation Trust

    Cambridge, United Kingdom

  • Douglas Hospital Research Centre

    Montreal, Canada

  • Foundation for Biomedical Research of the Gregorio Marañón Hospital (FIBHGM)

    Madrid, Spain

  • IRCCS Santa Lucia Foundation

    Roma, Italy

  • Institute of Psychiatry, Psychology & Neuroscience, King's College London

    London, United Kingdom

  • Ludwig Maximilian University Hospital

    München, Germany

  • MedUni Vienna, Department of Child and Adolescent Psychiatry

    Vienna, Austria

  • National and Kapodistrian University of Athens

    Athens, Greece

  • Oxford Health NHS Foundation Trust (OHFT)

    Oxford, United Kingdom

  • Psychiatric University Hospital (PUK)

    Zurich, Switzerland

  • Stichting Amsterdam UMC

    Amsterdam, Netherlands

  • University Hospital Turku

    Turku, Finland

  • University Medical Center Schleswig-Holstein

    Lübeck, Germany

  • University of Bari Aldo Moro

    Bari, Italy

  • University of Campania L. Vanvitelli

    Naples, Italy

  • University of Cologne, Faculty of Medicine and University Hospital of Cologne

    Cologne, Germany

  • University of Pavia

    Pavia, Italy

  • Vivantes Network for Health GmbH

    Berlin, Germany

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