Malaria drug combo under microscope: safety first
NCT ID NCT07470424
First seen Mar 26, 2026 · Last updated Jun 23, 2026 · Updated 15 times
Summary
This early-stage trial will give 24 healthy adults three different malaria drugs—piperaquine, pyronaridine, and artesunate—alone and together to see how they interact. Researchers will measure drug levels in the blood and watch for side effects. The goal is to learn about safety and dosing, not to treat malaria.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Medical Therapeutic Unit, Faculty of Tropical Medicine
Bangkok, 10400, Thailand
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
piperaquine, pyronaridine, and artesunate
What this could lead to
If successful, this study could help doctors understand how to combine these malaria drugs more safely and effectively.
What could go wrong
This is a very early, small study in 24 healthy people, not patients. It only looks at drug levels and safety, not whether the drugs cure malaria.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.