Malaria drug combo under microscope: safety first

NCT ID NCT07470424

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This early-stage trial will give 24 healthy adults three different malaria drugs—piperaquine, pyronaridine, and artesunate—alone and together to see how they interact. Researchers will measure drug levels in the blood and watch for side effects. The goal is to learn about safety and dosing, not to treat malaria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
piperaquine, pyronaridine, and artesunate
What this could lead to
If successful, this study could help doctors understand how to combine these malaria drugs more safely and effectively.
What could go wrong
This is a very early, small study in 24 healthy people, not patients. It only looks at drug levels and safety, not whether the drugs cure malaria.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MALARIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical Therapeutic Unit, Faculty of Tropical Medicine

    Bangkok, Bangkok, 10400, Thailand

More trials for these conditions

Other studies related to the condition(s) this trial covers.