Cannabis compound tested as boost for Toughest-to-Treat psychosis
NCT ID NCT07326124
Summary
This study is testing whether adding a purified cannabis compound called cannabidiol (CBD) can improve the effects of the antipsychotic drug clozapine for people with severe, treatment-resistant psychosis. About 250 participants who haven't responded well to clozapine alone will take either CBD or a placebo pill for 12 weeks, in addition to their regular clozapine treatment. Researchers will measure changes in symptoms, thinking, and quality of life to see if CBD helps.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Cambridgeshire and Peterborough NHS Foundation Trust
Cambridge, United Kingdom
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Charité Universitätsmedizin
Berlin, Germany
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Geha Mental Health Center
Petah Tikva, Israel
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Hospital General Universitario Gregorio Marañón
Madrid, Spain
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Hospital Universitario Virgen del Rocío
Seville, Spain
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Ludwig-Maximilian-University Munich
Munich, Germany
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National and Kapodistrian University of Athens
Athens, Greece
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Oxford Health NHS Foundation Trust
Oxford, United Kingdom
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Psychiatric University Hospital (PUK), Zurich
Zurich, Switzerland
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Shalvata Mental Health Center
Hod HaSharon, Israel
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Sheba Medical Centre
Ramat Gan, Israel
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Stichting Amsterdam UMC
Amsterdam, Netherlands
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University Hospital Cologne
Cologne, Germany
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University of Campania 'Luigi Vanvitelli'
Naples, Italy
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West London NHS Trust
London, United Kingdom
Conditions
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