Could an epilepsy drug quiet the overactive brain region behind psychosis?

This trial tests whether a single dose of levetiracetam, a drug used for epilepsy, can reduce overactivity in the hippocampus — a brain area linked to thinking and memory problems in psychosis. People aged 18–40 who are at risk of psychosis will take either the drug or a placebo before undergoing MRI scans that measure blood flow, brain activity, and chemical levels. The study also includes healthy volunteers for comparison. The goal is to see if rebalancing brain signals could lead to new early treatments for psychosis.