Prozac's brain effects under the microscope in healthy youth
NCT ID NCT07456501
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a week of Prozac (fluoxetine) changes decision-making and social thinking in 80 healthy people aged 18-24. Participants take either Prozac or a placebo, then complete tasks on emotion recognition, reward learning, and social exclusion. The goal is to better understand how antidepressants work in young brains, which could improve treatment for depression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fluoxetine (Prozac)
- What this could lead to
- If successful, this study could help doctors understand which young people might benefit most from antidepressants like Prozac.
- What could go wrong
- This is an early-stage study in healthy volunteers, not patients. It only lasts 7 days, so long-term effects or real-world benefits are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Oxford Department of Psychiatry
Oxford, OX3 7JX, United Kingdom
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