Major study aims to unlock the secrets of Treatment-Resistant depression
NCT ID NCT07189689
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will follow 2,000 adults with major depressive disorder or bipolar disorder to understand why some people get better with treatment and others do not. Researchers will collect information on symptoms, thinking abilities, genetics, metabolism, proteins, and immune markers. The goal is to improve diagnosis and treatment for mood disorders that are hard to treat.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify markers that predict treatment response, paving the way for more personalized and effective treatments for mood disorders.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results may take years to translate into clinical practice.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinical Research Facility, Warneford Hospital
Oxford, United Kingdom
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Other studies related to the condition(s) this trial covers.
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