Sun Yat-sen University

This study investigates whether infusions of bone marrow stem cells (CG-BM1) can safely help people with acute-on-chronic liver failure, a life-threatening condition where the liver suddenly stops working. The trial involves 90 adults and will test different doses of stem cells g…

This study tested a combination of three drugs—camrelizumab, apatinib, and chemotherapy (gemcitabine plus cisplatin)—in 49 people with advanced biliary tract cancer that could not be removed by surgery. The goal was to see if the combo is safe and how well it shrinks tumors. Resu…

This study tested whether taking anlotinib pills after initial chemotherapy can help keep advanced soft tissue sarcoma from growing. 49 adults with certain types of sarcoma took anlotinib daily. The goal was to see how long the cancer stayed stable and to check safety. Anlotinib …

This phase 2 trial tests a combination of two drugs—chidamide and toripalimab—in people with advanced soft-tissue sarcoma that has not responded to standard treatments. Chidamide is a pill that may help the immune system recognize cancer cells, while toripalimab is an immunothera…

This early-phase trial tested a personalized cell therapy for people with advanced bone or soft tissue sarcoma that had stopped responding to standard treatment. The therapy uses the patient's own immune cells, modified to better recognize and attack cancer cells carrying a speci…

This study tested a combination of two drugs, cadonilimab and regorafenib, in 36 adults with advanced liver cancer that had worsened after standard treatments. The goal was to see if the combo could slow cancer growth and how safe it was. Results may help develop better options f…

This phase 2 trial tested a combination of two drugs—anlotinib (a targeted therapy) and toripalimab (an immunotherapy)—in 70 people with advanced soft-tissue sarcoma that had stopped responding to standard treatment. The goal was to see if the combo could shrink tumors or slow di…

This study tested whether adding bevacizumab to a powerful four-drug chemotherapy regimen (FOLFOXIRI) could shrink liver tumors in people with colorectal cancer that had spread only to the liver and could not be removed surgically. The goal was to see if more patients could then …

This study tested a new surgical technique for esophageal cancer that avoids a large chest incision. 35 patients with early-stage cancer received this less invasive procedure. The goal was to see if it could lower complication rates while still effectively removing the cancer. Re…

This study tested whether adding an extra chemotherapy drug (capecitabine) after standard treatment helps people with advanced nasopharyngeal cancer that is likely to spread. 294 patients received either standard chemoradiotherapy alone or standard treatment plus capecitabine. Th…

This phase 3 trial tested whether giving only radiation therapy works as well as radiation plus chemotherapy for people with intermediate-risk nasopharyngeal cancer. The study enrolled 338 participants and used modern intensity-modulated radiation therapy (IMRT). The goal was to …

This study tested a combination of two drugs (cadonilimab and lenvatinib) given before surgery to 39 people with kidney cancer that was difficult to operate on while saving the kidney. The goal was to shrink the tumor enough to allow a partial, kidney-sparing surgery instead of r…

This study looked at 200 people with advanced liver cancer whose first treatment (bevacizumab plus sintilimab) stopped working. Researchers compared two second-line options: a PD-1 inhibitor combined with either lenvatinib or regorafenib. The goal was to see which combo works bet…

This phase 2 study tested a combination of three drugs in 46 people with a specific type of lung cancer (EGFR-mutated) that had spread to the lining of the brain and spinal cord (meningeal metastasis). The treatment included a high-dose targeted pill (furmonertinib), an intraveno…

This study tested a combination of two drugs, pamiparib and surufatinib, in 29 women with ovarian cancer that stopped responding to platinum chemotherapy and had previously taken PARP inhibitors. The goal was to see if the combo could control the cancer for at least 6 months. The…

This study tested a combination of an immunotherapy drug (anti-PD-1) and a chemotherapy drug (albumin-bound paclitaxel) in 27 people whose cervical cancer had returned or worsened after standard treatment. The goal was to see if the combination could shrink tumors and help patien…

This study tested a combination of two drugs, apatinib and etoposide, in 35 women with ovarian cancer that had stopped responding to platinum-based chemotherapy. The goal was to see if the combination could shrink tumors or slow disease progression. Participants took the drugs by…

This study tested whether adding a low-dose chemotherapy pill (capecitabine) to standard hormone therapy (aromatase inhibitor) helps women with a common type of advanced breast cancer live longer without the disease getting worse. The trial involved 263 women who had not received…

This study tested a combination of an immunotherapy drug (durvalumab) and chemotherapy delivered directly to the liver (HAIC) in 30 adults with advanced liver cancer that had spread into the main portal vein. The goal was to see if the combination could improve one-year survival.…

This study looked at liver cancer patients whose tumors shrank completely after non-surgical treatments like chemoembolization and immunotherapy. Researchers compared those who then had surgery to remove any remaining tissue versus those who simply watched and waited. The goal wa…

This study tested whether adding a liver-directed chemotherapy infusion (HAIC) to a standard drug combo (Gemox, lenvatinib, toripalimab) helps people with advanced bile duct cancer live longer without the disease getting worse. 96 patients took part. The goal was to see if the ex…

This study tested whether adding the antibiotic moxifloxacin to standard chemotherapy improves outcomes for people with operable breast cancer. 559 participants were randomly assigned to receive either moxifloxacin or a placebo alongside their chemo. The main goal was to see if t…

This study looked at 300 adults with high-risk liver cancer who received a combination of two drugs (atezolizumab and bevacizumab) plus chemotherapy infused directly into the liver artery. The goal was to see how well this treatment worked and how safe it was in everyday medical …

This study tested whether adding oral diabetes drugs (metformin/pioglitazone or sitagliptin) to a short-term insulin pump can improve long-term blood sugar control and help newly diagnosed type 2 diabetes patients achieve remission. 264 participants who were newly diagnosed, not …

This small, early-phase trial tested a combination of two drugs—cetuximab and capecitabine—as a maintenance treatment for people with a specific genetic type of advanced colorectal cancer (KRAS/BRAF wild-type). The main goals were to check safety, find the best dose, and see how …

This study tested an artificial intelligence platform that screens for cognitive dysfunction by analyzing eye movements. Over 1,500 participants, including people with various dementias and healthy individuals, took part. The AI aims to detect cognitive impairment and provide ref…

This study tested a new way to find small cancer spots in neck lymph nodes of people with nasopharyngeal cancer. Researchers combined MRI scans with a special ultrasound that uses a contrast agent. They aimed to create a better rule for spotting these tiny metastases. 348 patient…

This study tested a virtual peer agent—a friendly AI that talks with teens—to see if it can help them handle stressful life events. Fifty-five teens aged 14 to 25 used the agent for 4 weeks, having conversations about emotions, coping strategies, and support. Researchers checked …

This phase 3 trial tested whether ulinastatin, a drug that blocks certain enzymes, can reduce severe mouth sores caused by chemoradiotherapy in 179 patients with advanced nasopharyngeal cancer. Patients received either standard care or ulinastatin alongside their cancer treatment…

This study tested whether neurotropin, a drug that may protect nerves, can reduce the nerve damage caused by oxaliplatin chemotherapy in people with stage II or III colorectal cancer. The trial included 333 participants who had surgery and were about to start chemotherapy. Resear…

This study tested two Oclean sonic electric toothbrushes against a standard manual toothbrush to see which reduces extrinsic tooth stains best. Over 8 weeks, 129 adults brushed twice daily and had their stains measured using a standard index. The goal was to find out if the sonic…

This study looked at 252 adults having lung surgery to see if giving pain medicine in small bursts (programmed intermittent bolus) works better than a steady drip (continuous infusion). Both methods use an epidural, a common pain relief technique. The goal was to find which appro…

This completed study followed over 1,100 pregnant women in Guangzhou to see how their diet and nutrition during and after pregnancy relate to blood sugar problems like gestational diabetes. Researchers also tracked the children's growth, brain development, and allergies up to age…

This study looked at whether children with cancer who watch mukbang (eating shows) have better appetite during hospital treatment. Researchers tracked 179 children's eating habits and video watching over several days. The goal was to see if there's a link that could help improve …

This study looked at 103 research articles to compare the nutrients in breast milk from mothers who gave birth early (preterm) versus full-term. The goal was to see if there are differences in energy, protein, fat, and other nutrients. This is a review of existing studies, not a …

This completed phase 2 study tested whether a new type of PET scan (FAPI-PET/CT) can accurately predict if rectal cancer has completely disappeared after a combination of short-course radiation, immunotherapy, and chemotherapy. Fifty-two patients with locally advanced rectal canc…

This completed study used artificial intelligence to analyze data from 7,000 liver cancer patients. The goal was to create a tool that helps doctors predict liver function, treatment outcomes, and cancer spread. The tool aims to guide personalized decisions about surgery, chemoth…