New cocktail of drugs shows promise for tough bile duct cancer

NCT ID NCT05742750

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a combination of three drugs—camrelizumab, apatinib, and chemotherapy (gemcitabine plus cisplatin)—in 49 people with advanced biliary tract cancer that could not be removed by surgery. The goal was to see if the combo is safe and how well it shrinks tumors. Results could point to a new first-line treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

camrelizumab, apatinib, gemcitabine, cisplatin

What this could lead to

If successful, this combination could offer a new first-line treatment option for people with advanced biliary tract cancer, potentially improving tumor shrinkage and disease control.

What could go wrong

This is an early-phase, single-center trial with only 49 participants, so results may not apply broadly. The combination also carries risks of serious side effects from chemotherapy and immunotherapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cancer center of SunYat-sen University

    Guangzhou, Guangdong, 510060, China