New combo attack on tough liver cancer shows promise in Real-World study

NCT ID NCT07272265

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 300 adults with high-risk liver cancer who received a combination of two drugs (atezolizumab and bevacizumab) plus chemotherapy infused directly into the liver artery. The goal was to see how well this treatment worked and how safe it was in everyday medical practice. The study is already completed, and researchers are analyzing survival and tumor progression data from medical records across 10 hospitals in China.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Atezolizumab and bevacizumab (immunotherapy and anti-angiogenic drugs) plus liver artery infusion of FOLFOX chemotherapy
What this could lead to
If successful, this combination could offer a more effective first-line treatment option for patients with high-risk liver cancer that has spread to major blood vessels or bile ducts.
What could go wrong
This is a retrospective study, not a controlled trial, so results may be less reliable. The combination also carries risks of serious side effects from both immunotherapy and chemotherapy.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510000, China

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