Second Affiliated Hospital Of Nanchang University

This study tests whether a new triple therapy—spatially fractionated radiotherapy (SFRT), the immunotherapy drug tislelizumab, and standard chemotherapy—can shrink initially unresectable stage 3 non-small cell lung cancer enough to allow surgery. About 30 participants will receiv…

This study is testing a new treatment for dry eye disease. Researchers are transplanting healthy bacteria from one person's eye surface into the eyes of people with moderate to severe dry eye. The goal is to see if this can improve symptoms like dryness and discomfort. The study …

This study tests whether a 12-week course of semaglutide injections works better than a calorie-restricted diet for people with type 2 diabetes and fatty liver disease. About 100 adults aged 18-75 with a BMI of 25 or higher will be enrolled. Researchers will track changes in bloo…

This study tests whether adding the antidepressant olanzapine to standard immunotherapy can help people with advanced non-small cell lung cancer live longer. About 156 adults with a specific type of lung cancer (EGFR mutation-negative) will receive either immunotherapy alone or i…

This study tests a new way to treat large solid tumors that have come back or not responded to standard treatments. It combines a special type of radiation therapy with two immunotherapy drugs to help the immune system fight the cancer. The goal is to see if this approach is safe…

This study tests whether a probiotic called MR-61 can help slow the progression of myopia (nearsightedness) in children and teens aged 3 to 18. Researchers will compare changes in eyesight and eye length between those taking the probiotic and those taking a placebo over time. The…

This study tests a stronger dose of a targeted cancer pill (EGFR-TKI) combined with two other drugs for people with advanced lung cancer that has spread to the lining of the brain and is no longer responding to standard treatment. About 30 adults will receive this combination to …

This study looks at whether a procedure called superselective adrenal arterial embolization can improve blood vessel function in people with primary aldosteronism, a condition where the adrenal glands produce too much of the hormone aldosterone, leading to high blood pressure. Th…

This study tests whether a computer program (deep neural network) can accurately predict the best lens size and position for nearsighted people getting implantable contact lens surgery. About 326 adults aged 18-45 with stable nearsightedness will have their eye images analyzed by…

This study tests a nursing program designed to help patients take better care of themselves after surgery for varicose veins in the legs. About 104 adults who are having their first surgery for this condition will take part. The program focuses on teaching daily living skills, ma…

This study tests whether adding platelet-rich plasma and a long-acting painkiller to standard steroid injections during shoulder surgery can reduce pain and improve function. About 70 adults with torn rotator cuffs and shoulder stiffness will be followed for 12 months after surge…

This study tests a new device called the AccuSafe guidewire against the usual needle for a key step in treating atrial fibrillation (an irregular heartbeat). The goal is to see if the guidewire makes the procedure safer, faster, and reduces the need for X-rays. About 144 adults w…

This study is following 5,000 people who had a brain bleed from a burst aneurysm. Researchers are collecting data to find out which factors lead to complications, disability, or death. The goal is to build better prediction tools to help doctors and patients make informed decisio…

This study aims to understand what factors influence vision quality after SMILE laser eye surgery when a small piece of the lens is intentionally left inside the eye. Researchers will measure changes in higher-order aberrations (tiny vision imperfections) before and after surgery…

This study aims to create a smart computer model using deep learning to help doctors more accurately diagnose and predict recovery in people with spontaneous hemorrhagic stroke (bleeding in the brain). Researchers will analyze CT scans and medical data from 7,100 patients aged 8 …