Diabetes drug semaglutide takes on dieting in fatty liver showdown
NCT ID NCT07272343
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares weekly semaglutide injections to a calorie-restricted diet in 100 adults with type 2 diabetes and fatty liver disease. Over 12 weeks, researchers will measure changes in blood sugar, weight, inflammation, and liver fat. The goal is to see which approach works better and understand the underlying molecular mechanisms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
semaglutide
What this could lead to
If successful, this could show that semaglutide is more effective than dieting alone for controlling blood sugar and reducing liver fat in people with type 2 diabetes and fatty liver disease.
What could go wrong
This is a small, early-phase (Phase 4) study with only 100 participants over 12 weeks. Results may not apply to everyone, and semaglutide can cause side effects like nausea or vomiting.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Minde road No.1
RECRUITINGJiangxi, Nanchang, 330000, China
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••