New combo therapy aims to make inoperable lung cancer operable

NCT ID NCT07131319

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special radiation method (SFRT) given alongside immunotherapy (tislelizumab) and standard chemotherapy can shrink stage III lung tumors that cannot be surgically removed. The goal is to see if this combination makes more patients eligible for surgery. Thirty participants will receive the treatment and be monitored for side effects and surgical success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Spatially fractionated radiotherapy (SFRT), tislelizumab, carboplatin, pemetrexed, nab-paclitaxel
What this could lead to
If successful, this combination could help shrink hard-to-treat lung tumors enough to allow surgery, potentially improving long-term outcomes.
What could go wrong
This is a small, early-phase study (30 people) testing a new radiation technique plus immunotherapy and chemo, so side effects may be significant and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nanchang City, Jiangxi Province

    RECRUITING

    Nanchang, Jiangxi, 330000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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