Double-Drug attack targets tough lung cancer

NCT ID NCT07655622

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether combining two targeted drugs, vebreltinib and furmonertinib, can control advanced non-small cell lung cancer in people whose tumors have both an EGFR mutation and high PD-L1 expression. The study enrolls about 45 adults who have not received prior treatment for advanced disease. Researchers will monitor how long the cancer stays under control and track any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vebreltinib and furmonertinib

What this could lead to

If successful, this drug combination could offer a new first-line treatment option for people with a specific type of advanced lung cancer.

What could go wrong

This is an early-phase trial with a small number of participants, so results may not apply broadly. Side effects from combining two targeted therapies are not yet fully known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jianxi, 330006, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••