New combo injection aims to ease pain after rotator cuff surgery

NCT ID NCT07348016

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a long-acting painkiller (liposomal bupivacaine) to a standard steroid injection during shoulder surgery can improve recovery for people with rotator cuff tears and shoulder stiffness. About 70 adults will be randomly assigned to receive either the combo or the steroid alone. Researchers will track pain, shoulder function, and healing over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Liposomal Bupivacaine and Compound Betamethasone injection
What this could lead to
If it works, this could lead to a simple way to reduce pain and improve shoulder function after rotator cuff surgery, helping patients recover faster.
What could go wrong
This is a small, early-phase trial with only 70 participants, so results may not apply to everyone. The added drug may not provide significant benefit over the standard steroid alone.

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Conditions

The condition(s) this trial relates to.

frozen shoulder Rotator Cuff Injuries rotator cuff syndrome Tissue Adhesions

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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