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Could a simple score predict dementia in depressed seniors?

NCT ID NCT07676851

Recruiting now Knowledge-focused Sponsor: Second Affiliated Hospital of Nanchang University Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study aims to create a risk score that uses information from electronic medical records to predict the chance of developing dementia within 5, 9, or 13 years in older adults with depression. Researchers will analyze data from 44 participants aged 50 and older who have a depression diagnosis. No new treatments or tests are involved; the study only observes routine care to see if the risk score accurately identifies those at higher risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this tool could help doctors identify older adults with depression who are at high risk for dementia, enabling earlier monitoring or intervention.
What could go wrong
This is a small observational study in a specific Chinese population, so the risk score may not apply to other groups. It only predicts risk, not prevents or treats dementia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DEMENTIA (AD) CHINESE POPULATION DEMENTIA EXTERNAL VALIDATION LATE LIFE DEPRESSION (LLD) OBS E R OBSERVATIONAL COHORT STUDY PREDICTION RISK SCORES

Contacts and locations

Locations

  • Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

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