New procedure could replace pills for Hormone-Driven high blood pressure
NCT ID NCT05561361
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a procedure called superselective adrenal artery embolization can improve blood vessel function in people with primary aldosteronism, a condition where the adrenal glands make too much of the hormone aldosterone, causing high blood pressure. The procedure involves injecting a substance to block part of the adrenal gland, reducing hormone production. Researchers will compare this to standard treatment with the drug spironolactone in 200 adults aged 18-75.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- superselective adrenal artery embolization (a procedure that blocks part of the adrenal gland to reduce hormone secretion)
- What this could lead to
- If successful, this procedure could offer a less invasive alternative to long-term medication for controlling high blood pressure caused by primary aldosteronism.
- What could go wrong
- This is a relatively early study with 200 participants, and the procedure carries risks like bleeding or damage to the adrenal gland. It may not prove better than standard drug therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Second Affiliated Hospital of Nanchang University
RECRUITINGNanchang, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Sharper blood test could uncover hidden cause of high blood pressure
- New drug may offer safer option for Hormone-Driven high blood pressure