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Alcohol injection into adrenal tumors may offer surgery-free blood pressure control

NCT ID NCT07700472

Not yet recruiting Disease control Sponsor: Chongqing Medical University Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests a procedure that uses a thin needle guided by an endoscope to inject alcohol into a benign adrenal tumor that produces too much aldosterone, a hormone that raises blood pressure. The goal is to destroy the tumor without surgery. The trial enrolls 30 adults with left-sided aldosterone-producing adenomas who cannot or choose not to have surgery. Participants are followed for safety, tumor disappearance on scans, and biochemical and blood pressure improvements.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
endoscopic ultrasound-guided ethanol ablation
What this could lead to
If successful, this could offer a less invasive alternative to surgery for people with aldosterone-producing adenomas, potentially controlling high blood pressure and reducing medication needs.
What could go wrong
This is a small, early-stage study with only 30 participants, so results may not apply broadly. The procedure carries risks like bleeding, organ damage, or hypertensive emergencies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

adrenal cortex adenoma aldosterone-producing adrenal cortex adenoma hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALDOSTERONE-PRODUCING ADENOMA PRIMARY ALDOSTERONISM

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Choongqing, 400016, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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