Oslo University Hospital

This early-phase trial tests a cancer vaccine (Pseudovax) plus an immunotherapy drug (tislelizumab) in 10 adults with pseudomyxoma peritonei, a rare abdominal cancer that has returned or cannot be surgically removed. The vaccine targets tumors with a specific GNAS gene mutation, …

This study tests a Norwegian e-health program called DiaMester that helps adults with type 2 diabetes improve self-management and lose weight. The goal is to see if significant weight loss can lead to diabetes remission. About 99 participants will be randomly assigned to differen…

This study is for people with a type of liver cancer (intrahepatic cholangiocarcinoma) that cannot be removed by surgery. It compares two treatments delivered directly to the liver's blood supply—HAI-FUDR/DEX and SIRT—both given alongside standard chemotherapy. The goal is to shr…

This study compares two types of radiation therapy for people with slow-growing brain tumors (IDH-mutated gliomas). Proton therapy aims to better protect healthy brain tissue than standard photon therapy, but it's unclear if it's as effective at controlling the tumor. The trial w…

This study tests a new 5-day outpatient program called Temperament Based Therapy with Support (TBT-S) for adults with anorexia nervosa. Researchers want to see if adding TBT-S to standard care helps reduce eating disorder symptoms more than standard care alone. About 120 particip…

This study tests whether a higher dose of proton radiation can better control soft tissue sarcomas that cannot be surgically removed. About 40 adults in Norway will receive radiation over 4 weeks, with the highest dose focused on the tumor center. Researchers will also look at bl…

This study tests whether a personalized, 3-week course of proton or x-ray radiation before surgery can reduce long-term side effects for adults with soft tissue sarcoma. About 110 participants will have two radiation plans made, and a national team will choose the best one for ea…

This study tests whether a remote expert can guide a bedside ultrasound to accurately detect fluid buildup in the belly after liver surgery. About 40 patients will be scanned within 72 hours of surgery. The goal is to see if this remote method works as well as a standard ultrasou…

This study compares a new type of radiotherapy (dose painting) to standard radiotherapy for head and neck cancer. The goal is to see if the new approach causes fewer severe mouth ulcers one year after treatment. About 100 adults with certain head and neck cancers will take part, …

This study compares two types of talk therapy for teenagers with eating disorders. About 200 teens will receive either family-based treatment or enhanced cognitive behavior therapy. The goal is to see if one therapy works as well as the other in reducing eating disorder symptoms.

This study tests whether combining spinal cord stimulation with a rehabilitation program can reduce long-term nerve pain in the legs and improve daily function. Ten adults aged 18-60 with nerve pain lasting over 6 months will receive both treatments together. The goal is to see i…

This study tests a two-week intensive outpatient program for adults with PTSD. Up to 42 participants will receive daily trauma-focused therapy and be followed for 12 weeks. Researchers will measure changes in PTSD symptoms and quality of life using questionnaires and interviews. …

This study compares two treatments for adults aged 20-65 with chronic low back pain lasting at least a year: lumbar fusion surgery versus a multidisciplinary rehab program. The goal is to see which approach better reduces disability and improves daily life. Participants are rando…

This study observes about 1,950 patients with suspected sepsis in the emergency department. Researchers will analyze blood samples to see how well certain markers (like calprotectin) and rapid DNA tests can detect infections. The goal is to better understand sepsis and move towar…

This study uses a special X-ray technique (RSA) to precisely measure how children's leg bones grow after surgery to correct length differences or bowing. Ten children who have had or will have this surgery will be tracked to understand growth patterns and help doctors decide the …

This study is watching 300 people in Norway who have had a spontaneous coronary artery dissection (SCAD), a rare heart condition that mostly affects women. Researchers will track their health for one year using heart scans, blood tests, and questionnaires. The goal is to better u…

This study looks at the best way to remove bile duct stones in people having their gallbladder removed. About 340 adults in Norway will be watched to see how well two different stone-removal methods work, how safe they are, and what they cost. The goal is to find which approach w…

This pilot study tests a new instrument to help surgeons balance the knee's main ligament (MCL) during total knee replacement. The goal is to see if the tool makes the procedure more consistent and repeatable. About 40 adults with knee osteoarthritis who need a knee replacement w…

This pilot study aims to understand how adults with schizophrenia or related psychotic disorders experience a new type of talk therapy designed for self-disorders. Eight participants will receive the therapy and then be interviewed about their experience, including whether they f…

This study looks at how people with celiac disease react to gluten in liquid form (a shake) versus solid form (a cookie). Thirty adults on a gluten-free diet will take part, giving blood samples to measure immune markers like IL-2. The goal is to see if one form triggers a strong…