Which bariatric surgery wins? new trial pits SASI bypass against sleeve gastrectomy

NCT ID NCT05611697

Recruiting now Disease control Sponsor: Oslo University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two weight-loss surgeries—SASI bypass and sleeve gastrectomy—in 220 adults with severe obesity. The goal is to see which one leads to more weight loss and fewer problems like acid reflux. Participants will be randomly assigned to one of the two procedures and followed for changes in BMI and reflux symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgical procedure (SASI bypass or sleeve gastrectomy)
What this could lead to: If successful, this could show which surgery is better for long-term weight loss and reducing acid reflux in people with severe obesity.
What could go wrong: This is a randomized trial but not blinded, and results may not apply to everyone. Both surgeries carry risks like infection, leaks, or nutritional deficiencies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

morbid obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, MORBID

Contacts and locations

Locations

Oslo University Hospital
RECRUITING

Oslo, 4950, Norway
The Morbid Obesity Center, Vestfold Hospital Trust
RECRUITING

Tønsberg, Vestfold, 3103, Norway

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