Oslo University Hospital
Clinical trials sponsored by Oslo University Hospital, explained in plain language.
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Can seniors handle colon cancer chemo? new study investigates
Disease control CompletedThis study looked at how well people aged 75 and older with stage III colon cancer handle chemotherapy after surgery. Researchers measured changes in daily living activities, side effects, and quality of life. The goal is to better identify which older patients can benefit from c…
Phase: PHASE2 • Sponsor: Oslo University Hospital • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Light therapy may shield transplant patients from dangerous immune attack
Disease control CompletedThis study tested whether a procedure called extracorporeal photophoresis (ECP) could prevent graft-versus-host disease (GVHD) in 158 people receiving stem cell transplants for blood cancers. ECP involves treating a patient's blood with light before returning it to the body. The …
Phase: NA • Sponsor: Oslo University Hospital • Aim: Disease control
Last updated May 08, 2026 12:01 UTC
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Clot-Busting drug shows promise for sudden blindness in eye artery blockage
Disease control CompletedThis study tested whether a clot-dissolving medicine called tenecteplase can restore vision in people who suddenly lose sight due to a blocked artery in the eye. 81 adults with central retinal artery occlusion received either tenecteplase or a placebo within 4.5 hours of symptoms…
Phase: PHASE3 • Sponsor: Oslo University Hospital • Aim: Disease control
Last updated May 06, 2026 16:14 UTC
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Iron boost after valve replacement: a simple fix for tired hearts?
Symptom relief CompletedThis study looked at whether a single intravenous iron dose can improve exercise capacity in people with severe aortic stenosis and iron deficiency who are scheduled for valve replacement. About 100 participants received either iron or a placebo. The main goal was to see if iron …
Phase: PHASE2 • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated May 17, 2026 03:29 UTC
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Celiac sufferers find relief by cutting certain carbs
Symptom relief CompletedThis study looked at whether reducing FODMAPs—certain carbohydrates found in many foods—can ease persistent stomach symptoms in people with celiac disease who already follow a strict gluten-free diet. Researchers surveyed and then randomly assigned 80 adults to test a low FODMAP …
Phase: NA • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated May 17, 2026 03:25 UTC
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Wrist surgery patients may get better pain relief with lower dose of numbing drug
Symptom relief CompletedThis study looked at 80 adults having wrist fracture surgery to see if a lower concentration of the numbing medicine ropivacaine could reduce severe "rebound pain" when the numbness wears off. Participants received either a standard or a lower dose of the medicine in a nerve bloc…
Phase: PHASE4 • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Cancer pain study questions need for extra paracetamol pills
Symptom relief CompletedThis study looked at whether cancer patients already taking strong opioids (like morphine) still need paracetamol for pain relief. About 200 adults with advanced cancer who were on both drugs were randomly assigned to either keep taking paracetamol or switch to a placebo. The goa…
Phase: PHASE3 • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Stroke's hidden toll on eyesight revealed in new study
Knowledge-focused CompletedThis study looked at how often people have vision problems after a stroke. Researchers checked 127 stroke patients' eyesight in the hospital and again 3 months later. The goal was to learn more about these vision issues and find better ways to spot them.
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 03:30 UTC
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Celiac study aims to make Gluten-Free claims more reliable
Knowledge-focused CompletedThis study involved 33 adults with celiac disease who followed a strict gluten-free diet. Researchers gave them small amounts of different gluten types (wheat, barley, and hydrolyzed barley) in separate one-day challenges to see how their immune systems responded. The goal was to…
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 03:28 UTC
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Opioid study reveals how painkillers affect mood before surgery
Knowledge-focused CompletedThis study looked at how three common opioids (morphine, oxycodone, and fentanyl) affect feelings like anxiety, relaxation, and pain right before surgery. It also tracked how much opioid pain medicine patients used after surgery and what factors predicted long-term use or persist…
Phase: PHASE4 • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 03:27 UTC
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Knee implant movement measured to boost future designs
Knowledge-focused CompletedThis study looked at how stable a new knee implant (GMK Sphere) is in people with knee osteoarthritis. Researchers used a special X-ray technique to measure any tiny movements of the implant over 5 years. The goal was to gather information that could help design better, longer-la…
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 03:25 UTC
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New pain predictor could spare women unnecessary suffering after surgery
Knowledge-focused CompletedThis study tested a quick, one-minute checklist to identify women at high risk for severe pain after gynecologic day surgery. Researchers followed 487 women and checked if the tool could accurately predict who would have severe pain at home. The goal is to help doctors give bette…
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 03:24 UTC
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Knee implant stability under the microscope: new study checks uncemented design
Knowledge-focused CompletedThis study looked at how stable a new type of uncemented knee implant stays inside the body over time. Researchers followed 31 people with knee osteoarthritis who received the implant during knee replacement surgery. Using special X-ray techniques, they measured implant movement …
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Which drug is safer for the heart after delivery?
Knowledge-focused CompletedThis study looked at whether carbetocin is less harmful to the heart than oxytocin, two drugs given to women after childbirth to prevent bleeding. Researchers measured heart damage markers in 240 healthy pregnant women. The goal was to find which drug is safer, especially for wom…
Phase: PHASE4 • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Spine surgery study probes hidden bacteria in back pain
Knowledge-focused CompletedThis study looked for bacteria in the spine and bones of 200 people with chronic low back pain who were having surgery. Researchers collected tissue samples during surgery and used special genetic tests to find bacteria. The goal was to understand if bacteria play a role in back …
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Breath test could replace needles for monitoring anesthesia in kids
Knowledge-focused CompletedThis study checked if measuring propofol (an anesthesia drug) in children's breath can accurately show how much is in their blood. 32 children having eye surgery took part. Researchers compared breath levels with blood samples and brain activity monitors. The goal was to see if a…
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Brain-Wave tracking during surgery may speed recovery and protect memory
Knowledge-focused CompletedThis study tested whether using EEG brain-wave monitoring during general anesthesia helps doctors give just the right amount of medicine. The goal was to see if this approach reduces drug use, shortens time to wake up after surgery, and lowers the risk of short-term thinking prob…
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC