Brain drain: can shunt surgery reverse cognitive decline and frailty?

NCT ID NCT07642726

Completed Knowledge-focused Sponsor: Oslo University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows people with idiopathic normal pressure hydrocephalus (iNPH) who are already scheduled for shunt surgery. Researchers measure changes in thinking skills and frailty one year after the procedure to identify which patients are most likely to improve. The goal is to better predict who will benefit from this surgical treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ventriculoperitoneal shunt
What this could lead to: If successful, this could help doctors predict which patients with normal pressure hydrocephalus will benefit most from shunt surgery, improving treatment decisions.
What could go wrong: This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients, and some may not improve after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction dementia Frailty Mobility Limitation normal pressure hydrocephalus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH)

Contacts and locations

Locations

Department of Geriatric Medicine, Oslo University Hospital

Oslo, Norway

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