Can a simple drug help people with fluid on the brain walk better?

NCT ID NCT04975269

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether the drug acetazolamide can improve walking in people with normal pressure hydrocephalus (NPH), a condition where excess fluid in the brain causes trouble walking, thinking, and bladder control. Fifty adults with NPH were randomly assigned to receive either acetazolamide or a placebo until they had shunt surgery. The main goal was to see if the drug improved gait function.

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Conditions

The condition(s) this trial relates to.

normal pressure hydrocephalus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Clinical Neurophysiology, Neurosurgery and Neurology, Uppsala University Hospital

    Uppsala, Sweden