New study tests gentler brain surgery for older patients
NCT ID NCT07447479
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two surgical approaches for treating idiopathic normal pressure hydrocephalus (iNPH) in people aged 60 and older. One group will receive standard ventriculoperitoneal shunt surgery under general anesthesia, while the other will receive a lumbar-peritoneal shunt under local anesthesia with sedation. The goal is to see if the less invasive local-anesthesia option is just as effective at improving walking ability three months after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- shunt surgery (ventriculoperitoneal or lumbar-peritoneal)
- What this could lead to
- If the local-anesthesia approach works as well as general anesthesia, it could offer a safer, less invasive surgical option for older patients with normal pressure hydrocephalus.
- What could go wrong
- This is a Phase 4 trial that hasn't started recruiting yet. The local-anesthesia procedure may not improve walking as much as the standard surgery, and there are always risks with any brain surgery, such as infection or bleeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Nadogaya Hospital
Kashiwa, Chiba, 277-0084, Japan
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Other studies related to the condition(s) this trial covers.
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