Blood 'bath' with light may stop transplant complication
NCT ID NCT03204721
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a procedure called extracorporeal photophoresis (ECP) could prevent graft-versus-host disease (GVHD) in 158 people receiving stem cell transplants for blood cancers. ECP involves removing white blood cells, treating them with a light-sensitive drug and UV light, then returning them to the patient. The goal was to see if this could lower the chance of GVHD, a serious complication where donor cells attack the patient's body.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
extracorporeal photophoresis (ECP) with 8-methoxypsoralen and ultraviolet A light
What this could lead to
If it works, ECP could become a standard preventive treatment to reduce the risk of graft-versus-host disease after stem cell transplants.
What could go wrong
This is a completed study, but results are not yet widely confirmed. ECP is a complex procedure and may not work for everyone. The trial was not blinded, which could bias results.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Tobias Gedde-Dhl
Oslo, Norway