Fluid bolus study reveals how IV fluids impact heart and brain in low blood volume
NCT ID NCT05705115
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study in 15 healthy volunteers tested how a small amount of Ringer's acetate (a common IV fluid) affects heart function and brain blood flow when blood volume is low. Participants were given the fluid during both normal and low blood volume conditions (simulated using lower body suction). The goal was to measure how long the fluid's effects last. The findings may help guide fluid therapy in hospitals.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ringer's acetate (intravenous fluid)
- What this could lead to
- If successful, this could help doctors better understand how and when to give IV fluids to patients with low blood volume, improving treatment decisions.
- What could go wrong
- This is a small, early-phase study in healthy volunteers, not patients. Results may not apply to real-world medical situations, and the fluid's effects may be short-lived.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Oslo University Hospital
Oslo, Oslo, 0586, Norway
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