Can ultrasound help doctors give the right amount of fluids in septic shock?

NCT ID NCT06043505

Completed Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a specific ultrasound-based algorithm could help doctors better manage fluids in patients with septic shock. The trial involved 136 intensive care patients and compared the algorithm to standard care over the first 4 days. The goal was to see if the algorithm could reduce the risks of giving too much or too little fluid.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ultrasound Hemodynamic Algorithm (UHA)
What this could lead to: If successful, this could provide a standardized, non-invasive way to guide fluid therapy in septic shock, potentially reducing complications from fluid overload or depletion.
What could go wrong: This is a small pilot study (136 patients) that is already completed, so results may not be definitive or widely applicable. The algorithm may not improve outcomes compared to standard care.

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Conditions

The condition(s) this trial relates to.

toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMODYNAMIC INSTABILITY SHOCK, SEPTIC

Contacts and locations

Locations

CHU de Nimes

Nîmes, 30029, France

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