Proton beam boost: new hope for inoperable sarcomas?

NCT ID NCT07173972

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a higher dose of proton radiation can better control inoperable soft tissue sarcomas without increasing side effects. Forty adults with these rare tumors will receive targeted radiation over 4 weeks. Researchers will also look at blood and imaging markers to predict who responds best.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Proton radiotherapy
What this could lead to
If successful, this could offer a more effective radiation option for patients with inoperable soft tissue sarcoma, potentially improving tumor control without increasing side effects.
What could go wrong
This is a small, early-phase (Phase 2) study with only 40 participants, so results may not apply to all patients. The higher radiation dose could also cause unexpected side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Haukeland University Hospital

    NOT_YET_RECRUITING

    Bergen, Norway

  • Oslo University Hospital

    RECRUITING

    Oslo, Norway

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