Smart radiation aims to cut severe mouth sores in head and neck cancer

NCT ID NCT06297902

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares standard radiation therapy to a newer method called dose painting for people with head and neck cancer. The goal is to see if dose painting causes fewer severe mouth ulcers one year after treatment. About 100 participants will be randomly assigned to receive either standard or experimental radiation. The experimental approach gives a higher dose to the most active part of the tumor while aiming to spare healthy tissue.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma hypopharynx cancer larynx cancer nasal cavity and paranasal sinus carcinoma oral cavity cancer oropharyngeal carcinoma radiation injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Haukeland University Hospital

    RECRUITING

    Bergen, N-5021, Norway

    Contact

  • Oslo University Hospital

    RECRUITING

    Oslo, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Olavs Hospital

    NOT_YET_RECRUITING

    Trondheim, N-7006, Norway

    Contact