Montefiore Medical Center

This study tests a low-dose weekly combination of two approved drugs, decitabine and venetoclax, for people with bone marrow cancers like MDS, AML, and CMML. The goal is to see if this gentler schedule can keep patients on treatment longer by reducing side effects. About 91 adult…

This study looks at two methods doctors use to help patients breathe during a cardiac arrest (when the heart stops). One method uses a tube placed in the windpipe, the other uses a mask-like device in the throat. The goal is to see which approach helps patients survive longer wit…

This early-phase study tests a drug called venetoclax combined with standard chemotherapy for adults newly diagnosed with acute myeloid leukemia (AML) or advanced myelodysplastic syndrome (MDS). The goal is to find the safest dose and see how well the combination works. About 99 …

This study aims to find the most accurate cortisol levels to diagnose adrenal insufficiency, a condition where the body doesn't make enough cortisol. Researchers will test 90 healthy volunteers and patients with known adrenal insufficiency using a more specific cortisol assay. Th…

This study tests a structured psychological support program for teenagers aged 10-19 who are having surgery for scoliosis. The program is based on cognitive behavioral therapy and aims to reduce anxiety, depression, and pain-related distress before and after the operation. Resear…

This study is a global registry that will follow 800 people who receive a new, less invasive heart valve replacement for a leaky tricuspid valve (tricuspid regurgitation). The goal is to learn how safe and effective the procedure is, and to understand complications like the need …

This study looks at how social factors like insurance and medication adherence impact quality of life in Hispanic and Black patients with inflammatory bowel disease (IBD). Researchers will survey 400 adults with IBD to understand these links. The goal is to find ways to improve h…

This study is testing whether cancer patients will regularly use a mobile app called RestoreMe to help with diet, nutrition, and activity during their treatment. About 50 patients with various cancers who are receiving radiation therapy will be asked to use the app. The main goal…